GADOLINIUM DTPA Meaning and
Definition
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Gadolinium DTPA, also known as gadopentetate dimeglumine, is a chemical compound used as a contrast agent in magnetic resonance imaging (MRI) procedures. It consists of a chelating agent, diethylenetriamine pentaacetic acid (DTPA), and the rare earth element gadolinium.
As a contrast agent, gadolinium DTPA enhances the visibility of blood vessels, organs, and tissues during MRI scans. It is administered intravenously and quickly distributes throughout the body. Due to its paramagnetic properties, it has a high affinity for binding to albumin and stays within the blood vessels for an extended period of time. This extended presence enhances the visibility and detection of abnormalities or diseases during imaging.
The gadolinium ion in gadolinium DTPA is highly effective at altering the relaxation properties of nearby water molecules, leading to improved image quality. It shortens the relaxation times of protons in tissues, which results in an increased signal intensity on MRI scans. This contrast enhancement helps physicians identify and differentiate tissues with greater accuracy.
While gadolinium DTPA is generally considered safe and well-tolerated, it should be used with caution in patients with impaired kidney function. There have been rare reports of a serious condition known as nephrogenic systemic fibrosis (NSF) in patients with severe renal dysfunction, who have received multiple doses of gadolinium-based contrast agents. Therefore, appropriate risk-benefit assessments are necessary before administration, and healthcare professionals must closely monitor patients for any adverse reactions or complications.
Common Misspellings for GADOLINIUM DTPA
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Etymology of GADOLINIUM DTPA
The word "Gadolinium DTPA" derives from two main components: "gadolinium" and "DTPA".
1. Gadolinium: Gadolinium is a chemical element named after the Finnish chemist Johan Gadolin. Johan Gadolin was the first person to isolate the element in 1880. The term "gadolinium" is derived from his surname.
2. DTPA: DTPA is an acronym for Diethylenetriaminepentaacetic acid. It is a synthetic organic compound used in various applications, including as a chelating agent in medical diagnostics. The DTPA acronym is derived from the structural components of the compound, where "D" represents diethylene, "T" refers to triamine, "P" represents pentaacetic, and "A" denotes acid.
