How Do You Spell 25 HYDROXYVITAMIN D(3) 1 ALPHA HYDROXYLASE?

Pronunciation: [twˈɛntifˈa͡ɪv hˈa͡ɪdɹəksˌɪvɪtˌamɪn dˈiː θɹˈiː wˈɒn ˈalfə hˈa͡ɪdɹəksˌɪle͡ɪs] (IPA)

The spelling of "25 Hydroxyvitamin D(3) 1 alpha Hydroxylase" can be explained using the International Phonetic Alphabet (IPA), a standardized system for representing the sounds of spoken language. The first part, "25 Hydroxyvitamin D(3)", is pronounced /twɛn.ti faɪ haɪ.drɑksi vɪtəmɪn di(θ)riː wʌn ælfə/ and refers to a type of vitamin D. The second part, "1 alpha Hydroxylase", is pronounced /wʌn ælfə haɪ.drɑksə.leɪz/ and refers to an enzyme responsible for activating vitamin D in the body. The spelling reflects the specific chemical structure and function of these compounds.

25 HYDROXYVITAMIN D(3) 1 ALPHA HYDROXYLASE Meaning and Definition

  1. 25 Hydroxyvitamin D(3) 1 alpha Hydroxylase is an enzyme found primarily in the kidneys that plays a vital role in regulating the levels of active vitamin D in the body. It is responsible for converting 25-hydroxyvitamin D(3) (calcidiol) into its active form known as 1,25-dihydroxyvitamin D(3) (calcitriol).

    Calcidiol, the precursor molecule, is produced in the liver through the hydroxylation of vitamin D(3) derived from dietary sources or synthesized in the skin upon exposure to sunlight. Once transported to the kidneys, 25 Hydroxyvitamin D(3) 1 alpha Hydroxylase acts upon calcidiol, catalyzing a hydroxylation reaction at the 1-alpha position to form calcitriol.

    Calcitriol is the hormonally active form of vitamin D, and its functions extend beyond calcium and phosphate homeostasis. It acts as a transcription factor, influencing the expression of genes involved in cellular differentiation, proliferation, and immune responses.

    The activity of 25 Hydroxyvitamin D(3) 1 alpha Hydroxylase is tightly regulated by various factors, including parathyroid hormone (PTH), fibroblast growth factor-23 (FGF-23), and calcium levels. PTH stimulates the production of the enzyme, while FGF-23 and excess levels of calcitriol downregulate its synthesis.

    Deficiencies or dysregulation of 25 Hydroxyvitamin D(3) 1 alpha Hydroxylase can lead to inadequate production of active vitamin D, resulting in conditions such as rickets, osteomalacia, and impaired calcium and phosphate metabolism.

Common Misspellings for 25 HYDROXYVITAMIN D(3) 1 ALPHA HYDROXYLASE

  • 15 hydroxyvitamin d(3) 1 alpha hydroxylase
  • q5 hydroxyvitamin d(3) 1 alpha hydroxylase
  • w5 hydroxyvitamin d(3) 1 alpha hydroxylase
  • 35 hydroxyvitamin d(3) 1 alpha hydroxylase
  • 24 hydroxyvitamin d(3) 1 alpha hydroxylase
  • 2r hydroxyvitamin d(3) 1 alpha hydroxylase
  • 2t hydroxyvitamin d(3) 1 alpha hydroxylase
  • 26 hydroxyvitamin d(3) 1 alpha hydroxylase
  • 25 gydroxyvitamin d(3) 1 alpha hydroxylase
  • 25 bydroxyvitamin d(3) 1 alpha hydroxylase
  • 25 nydroxyvitamin d(3) 1 alpha hydroxylase
  • 25 jydroxyvitamin d(3) 1 alpha hydroxylase
  • 25 uydroxyvitamin d(3) 1 alpha hydroxylase
  • 25 yydroxyvitamin d(3) 1 alpha hydroxylase
  • 25 htdroxyvitamin d(3) 1 alpha hydroxylase
  • 25 hgdroxyvitamin d(3) 1 alpha hydroxylase
  • 25 hhdroxyvitamin d(3) 1 alpha hydroxylase
  • 25 hudroxyvitamin d(3) 1 alpha hydroxylase
  • 25 h7droxyvitamin d(3) 1 alpha hydroxylase
  • 25 h6droxyvitamin d(3) 1 alpha hydroxylase

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