ANTIHAEMOPHILIC FACTOR Meaning and
Definition
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Antihaemophilic factor, also known as factor VIII, is a glycoprotein involved in the clotting process of blood. It is primarily responsible for enabling blood to form clots by acting as a cofactor in the coagulation cascade. This factor plays a paramount role in preventing excessive bleeding and ensures the stability and integrity of blood vessels.
Antihaemophilic factor is particularly vital for individuals with haemophilia A, a hereditary bleeding disorder characterized by a deficiency or dysfunction of this clotting factor. In these individuals, a suitable therapeutic intervention is often required to compensate for the low levels of this factor. Such replacement therapy primarily involves the administration of exogenous antihaemophilic factor to restore its concentration within the bloodstream.
The development and commercialization of recombinant and blood-derived antihaemophilic factor concentrates have revolutionized the management of haemophilia A. These therapies, available as intravenous infusions, provide artificial antihaemophilic factor to individuals with haemophilia A, effectively enhancing their blood clotting abilities. By replenishing the missing or dysfunctional factor, antihaemophilic factor concentrates act as a bridge to facilitate normal clotting, reducing the risk of spontaneous bleeding and assisting in the treatment of bleeding episodes or surgical interventions.
Moreover, antihaemophilic factor concentrates may be manufactured from human plasma or produced through recombinant technology, with the latter being engineered using mammalian cell lines to produce a biologically active clotting factor. This ensures a safe, reliable, and efficient supply of antihaemophilic factor, aiding in the effective management of haemophilia A.
Common Misspellings for ANTIHAEMOPHILIC FACTOR
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Etymology of ANTIHAEMOPHILIC FACTOR
The word "Antihaemophilic Factor" is derived from a combination of Latin and Greek roots.
1. "Anti-" is a prefix derived from Greek meaning "against" or "opposed to".
2. "Haemophilic" is an adjective derived from the Latin word "haemophilus", which means "blood-loving". This term is used to describe a medical condition called "hemophilia", characterized by a deficiency in the blood's ability to clot.
3. "Factor" is a noun derived from the Latin word "facere", meaning "to do" or "to make". In medical terminology, "factor" refers to a substance that is responsible for a particular biological or chemical process.
Therefore, "Antihaemophilic Factor" can be understood as a compound term that references a substance or factor used to counteract or oppose hemophilia, a condition characterized by impaired blood clotting.
Similar spelling word for ANTIHAEMOPHILIC FACTOR
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