AQUAPORINS Meaning and
Definition
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Aquaporins are a group of specialized membrane proteins that facilitate the transport and regulation of water molecules across cell membranes in living organisms. These proteins play a crucial role in maintaining water balance and osmotic homeostasis in cells and tissues.
Aquaporins are responsible for the well-regulated movement of water across biological membranes. They have a distinctive structure, typically consisting of six membrane-spanning helices, forming a central pore through which water molecules can pass. The specific arrangement of amino acids within the structure of aquaporins enables them to selectively allow the passage of water molecules while preventing the movement of other molecules, such as ions or solutes.
These proteins are found in various organs and tissues throughout the body, including the kidneys, lungs, eyes, and brain. They are essential for numerous physiological processes, including urine formation, fluid secretion, tear production, and maintenance of cell volume. Aquaporins contribute to the efficiency and speed of water transport, allowing cells and tissues to quickly respond to changes in water availability.
Mutations or dysfunctions in aquaporins can result in various disorders and diseases, such as nephrogenic diabetes insipidus, certain types of cataracts, and some neurological conditions. Understanding the function and regulation of aquaporins is of great interest in medical and pharmaceutical research, as targeting these proteins can potentially provide therapeutic avenues for conditions related to water dysregulation, hydration, and edema.
Common Misspellings for AQUAPORINS
Etymology of AQUAPORINS
The word "aquaporins" is derived from the Latin word "aqua", which means water, and the word "porin", which refers to a proteinaceous channel. Thus, when combined, "aquaporins" means water channels or water pores.
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