ARYLSULFATASE B Meaning and
Definition
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Arylsulfatase B is an enzyme that plays a crucial role in the metabolism and degradation of sulfated compounds in the body. It is a member of the arylsulfatase family of enzymes and is specifically responsible for the hydrolysis of a class of molecules called sulfated glycosaminoglycans (GAGs).
GAGs are long, unbranched polysaccharides consisting of repeating disaccharide units. They are found in various tissues and organs, particularly in connective tissues, and are essential for their normal structure and function. However, for these GAGs to be effectively utilized and recycled in the body, they must undergo enzymatic degradation.
Arylsulfatase B specifically cleaves the sulfate group from the GAGs, enabling further breakdown and recycling of the sugar units. This enzyme is primarily active in the lysosomes, which are compartments within cells involved in the breakdown of various substances. Deficiencies or mutations in the arylsulfatase B gene can result in a rare genetic disorder called mucopolysaccharidosis type VI (MPS VI), characterized by the buildup of sulfated GAGs in various tissues and organs.
The catalytic activity of arylsulfatase B is critical for maintaining normal cellular function and preventing the accumulation of sulfated GAGs, which can lead to a wide range of clinical symptoms and organ dysfunction. The enzyme's activity is tightly regulated, and its deficiency can lead to significant impairments in connective tissues, bones, joints, and vital organs. Adequate levels of arylsulfatase B are essential for the proper metabolism and degradation of sulfated compounds in the body.
Common Misspellings for ARYLSULFATASE B
- zrylsulfatase b
- srylsulfatase b
- wrylsulfatase b
- qrylsulfatase b
- aeylsulfatase b
- adylsulfatase b
- afylsulfatase b
- atylsulfatase b
- a5ylsulfatase b
- a4ylsulfatase b
- artlsulfatase b
- arglsulfatase b
- arhlsulfatase b
- arulsulfatase b
- ar7lsulfatase b
- ar6lsulfatase b
- aryksulfatase b
- arypsulfatase b
- aryosulfatase b
- arylaulfatase b
Etymology of ARYLSULFATASE B
The word "Arylsulfatase B" is a scientific term that is derived from two main components: "aryl" and "sulfatase B".
1. Aryl: The term "aryl" is derived from the word "aromatic". It refers to a type of organic compound that contains one or more aromatic rings in its structure. The prefix "aryl" is commonly used in chemistry to describe different substituents or functional groups attached to an aromatic ring. In this context, "aryl" likely refers to a specific type of compound or structure related to the enzymatic function or classification of Arylsulfatase B.
2. Sulfatase B: The term "sulfatase B" refers to a specific enzyme that belongs to the sulfatase family and is classified as subtype B.
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