How Do You Spell BOMBESIN?

Pronunciation: [bˈɒmɪsˌɪn] (IPA)

Bombesin is a neuropeptide that occurs naturally in the human body. The spelling of this word follows the International Phonetic Alphabet (IPA), which is used to transcribe sounds in language. The initial consonant sound in bombesin is a bilabial consonant [b], followed by the vowel [ɑ]. The second consonant sound in the word is a nasal consonant [m], followed by the vowel [ɛ]. The final consonant sound is a fricative [z], followed by the vowel [ɪ] and the nasal consonant [n]. The correct pronunciation is "bom-beh-sin" with the emphasis on the second syllable [be].

BOMBESIN Meaning and Definition

1. Bombesin is a neuropeptide hormone that belongs to the bombesin family, which is widely distributed in the nervous system and various peripheral tissues of vertebrates. It was first discovered in the skin of frogs and later found to be present in mammals, including humans. Bombesin acts as a neurotransmitter or as a neuromodulator in the central nervous system and is also involved in the regulation of various physiological processes.

   As a neuropeptide, bombesin plays a crucial role in the regulation of eating behavior, satiety, and energy homeostasis. It is known to stimulate the release of gastrin-releasing peptide (GRP) and activated GRP receptors in the gastrointestinal tract, leading to the release of gastrointestinal hormones and regulating gastric acid secretion and motility. Additionally, it is involved in the regulation of other hormones such as insulin, glucagon, and growth hormone.

   Bombesin is also implicated in various pathological conditions, including cancer. It interacts with bombesin receptors that are highly expressed in certain cancer cells, such as lung, prostate, and breast cancer, promoting tumor growth, angiogenesis, and metastasis. Due to this potential therapeutic relevance, bombesin has been studied for its role as a target in cancer treatment.

   In summary, bombesin is a neuropeptide hormone that plays a vital role in the regulation of eating behavior, energy homeostasis, and hormone release. It has potential implications in various physiological processes and pathological conditions, particularly in cancer.

Common Misspellings for BOMBESIN

• vombesin
• nombesin
• hombesin
• gombesin
• bimbesin
• bkmbesin
• blmbesin
• bpmbesin
• b0mbesin
• b9mbesin
• bonbesin
• bokbesin
• bojbesin
• bomvesin
• bomnesin
• bomhesin
• bomgesin
• bombwsin
• bombssin
• bombdsin

Etymology of BOMBESIN

The word "Bombesin" is derived from the Latin term "bombus", which means "buzz" or "booming noise". It originally referred to a substance extracted from the skin of a frog species called Bombina bombina. Bombesin was initially discovered and isolated from the skin secretions of these frogs in the mid-1970s. Due to its biological activities and functions, it was named "Bombesin" as it was akin to the buzzing noise or call of the frogs.