How Do You Spell BUTHIONINE SULFOXIMINE?

Pronunciation: [bˈʌθɪˌɒna͡ɪn sʌlfˈɒksɪmˌiːn] (IPA)

Buthionine Sulfoximine is a chemical compound commonly used in biomedical research. The spelling of this word can be explained using IPA phonetic transcription. The first syllable "bu-" is pronounced as "bʌ", followed by "thi" which is pronounced as "θaɪ". The third syllable "o-" is pronounced as "əʊ", and "nine" is pronounced as "naɪn". The second part, "sulfoximine", can be broken down into "sul" pronounced as "sʌl", "fox" pronounced as "fɒks", and "imine" pronounced as "ɪmiːn". Thus, the complete pronunciation of Buthionine Sulfoximine is "bʌθaɪəʊnaɪnsʌlfɒksɪmiːn".

BUTHIONINE SULFOXIMINE Meaning and Definition

1. Buthionine Sulfoximine (BSO) is a small molecule compound and a potent inhibitor of glutathione synthesis. It is derived from the naturally occurring amino acid cysteine and was first synthesized in the 1970s. BSO acts primarily by blocking the enzyme gamma-glutamylcysteine synthetase, which is the rate-limiting step in the synthesis of glutathione, a vital antioxidant and detoxifying agent in cells.

   Inhibition of glutathione synthesis by BSO leads to a decrease in intracellular levels of glutathione, resulting in diminished cellular protection against oxidative stress and increased susceptibility to cell damage. BSO has been extensively used as a research tool to study the physiological functions of glutathione in various biological systems.

   Due to its ability to deplete cellular glutathione levels, BSO has emerged as a potential therapeutic agent in cancer treatment. Cancer cells often exhibit higher levels of oxidative stress compared to normal cells. By further reducing glutathione levels in cancer cells, BSO could potentially enhance the effectiveness of chemotherapy drugs that rely on the generation of reactive oxygen species for their cytotoxic activity. Additionally, BSO has been investigated in combination with other drugs for its potential role in sensitizing cancer cells to radiation therapy.

   Overall, Buthionine Sulfoximine is a compound that inhibits glutathione synthesis, leading to decreased cellular protection against oxidative stress and potential applications in cancer therapy.

Common Misspellings for BUTHIONINE SULFOXIMINE

• vuthionine sulfoximine
• nuthionine sulfoximine
• huthionine sulfoximine
• guthionine sulfoximine
• bythionine sulfoximine
• bhthionine sulfoximine
• bjthionine sulfoximine
• bithionine sulfoximine
• b8thionine sulfoximine
• b7thionine sulfoximine
• burhionine sulfoximine
• bufhionine sulfoximine
• bughionine sulfoximine
• buyhionine sulfoximine
• bu6hionine sulfoximine
• bu5hionine sulfoximine
• butgionine sulfoximine
• butbionine sulfoximine
• butnionine sulfoximine
• butjionine sulfoximine

Etymology of BUTHIONINE SULFOXIMINE

The word "Buthionine Sulfoximine" is a chemical compound name, and its etymology can be broken down as follows:

1. Buthionine: The term "buthionine" is derived from two components - "but(hyl)" and "ionine".

But(hyl)" originates from the alkyl group called butyl, which is a four-carbon straight-chain alkyl group. It is derived from the word "butane", a four-carbon hydrocarbon.Ionine" likely refers to or is influenced by "ion", which is an electrically charged particle.

2. Sulfoximine:

Sulfoximine" is a compound formed by combining "sulfo-" and "imine".Sulfo-" is derived from "sulfur" and refers to the presence of a sulfur atom in the compound.