How Do You Spell CAFFEINE DEMETHYLASE?

Pronunciation: [kˈafiːn dˈɛmiːθˌɪle͡ɪs] (IPA)

Caffeine Demethylase is an enzyme responsible for breaking down caffeine in the body. The phonetic transcription for this word in IPA is /kæˈfiːn diːˈmɛθɪleɪz/. The initial syllable "caf" is pronounced with a "k" sound followed by a long "a" sound, while the second syllable "feine" has a long "e" sound followed by a schwa sound. The final syllable "ase" is pronounced with a long "a" sound followed by an "s" sound, and the "methyl" part is pronounced with a long "e" sound and a "th" sound. Overall, the spelling of this word represents each sound in a logical order.

CAFFEINE DEMETHYLASE Meaning and Definition

1. Caffeine demethylase is an enzyme that plays a crucial role in the metabolism and breakdown of caffeine in various organisms, including humans. This enzyme is responsible for the demethylation of caffeine, which involves the removal of a methyl group from the caffeine molecule. Demethylation allows for the subsequent breakdown and elimination of caffeine from the body.

   In the human body, caffeine is primarily metabolized in the liver, where it undergoes a series of enzymatic reactions, including demethylation. Caffeine demethylase, also known as CYP1A2, is the key enzyme involved in this process. It belongs to the cytochrome P450 superfamily of enzymes, which are responsible for metabolizing a wide range of substances, including drugs, toxins, and endogenous compounds.

   Caffeine demethylase converts caffeine into three primary metabolites: paraxanthine, theobromine, and theophylline. These metabolites have different effects on the body and contribute to the overall metabolism and elimination of caffeine.

   Variations in the gene that encodes for caffeine demethylase can influence an individual's metabolism of caffeine. Some individuals have genetic variations that result in a slower metabolism of caffeine, leading to prolonged effects and increased sensitivity to its stimulant properties. Conversely, others may have genetic variations that enhance the activity of caffeine demethylase, resulting in a more rapid metabolism and reduced sensitivity to the effects of caffeine.

Common Misspellings for CAFFEINE DEMETHYLASE

• xaffeine demethylase
• vaffeine demethylase
• faffeine demethylase
• daffeine demethylase
• czffeine demethylase
• csffeine demethylase
• cwffeine demethylase
• cqffeine demethylase
• cadfeine demethylase
• cacfeine demethylase
• cavfeine demethylase
• cagfeine demethylase
• catfeine demethylase
• carfeine demethylase
• cafdeine demethylase
• cafceine demethylase
• cafveine demethylase
• cafgeine demethylase
• cafteine demethylase
• cafreine demethylase

Etymology of CAFFEINE DEMETHYLASE

The word "caffeine demethylase" is composed of two parts: "caffeine" and "demethylase".

1. Caffeine: The word "caffeine" is derived from the French word "caféine", which was coined in 1820. It comes from the French word "café", meaning coffee. The French word was derived from the German word "Kaffee", which is ultimately derived from the Arabic word "qahwah". "Qahwah" referred to a type of wine in Arabic, but it evolved to specifically mean "coffee" as the drink became popular.

2. Demethylase: The term "demethylase" is a combination of two parts: "de-" and "methylase". The prefix "de-" means to remove or reverse, while "methylase" refers to an enzyme that adds or removes methyl groups from molecules.