How Do You Spell CBZ?

Pronunciation: [sˌiːbˌiːzˈɛd] (IPA)

CBZ, also known as carbobenzoxy, is a commonly used protective group in organic chemistry synthesis. The spelling of CBZ is phonetically represented as /kɑrboʊˈbɛnzɑksi/ in IPA. The word is pronounced with the 'carbo' portion pronounced as 'car-bow,' while the 'benzoxy' portion is pronounced as 'ben-zock-see.' The CBZ protective group is utilized to safeguard amines from unwanted reactions while the rest of the molecule is being synthesized, making it a crucial tool in the field of organic chemistry.

CBZ Meaning and Definition

CBZ, also known as "carbobenzyloxy," is an abbreviation for a chemical group called "benzyloxycarbonyl." It is frequently used in organic chemistry synthesis and protection of sensitive functional groups during chemical reactions.

CBZ is a molecular moiety that can be attached to various organic compounds to stabilize and protect them from undesired reactions. It refers to a carbamate group, specifically a benzyloxycarbonyl group, which is formed by replacing the hydrogen atom of a carboxylic acid or amine with a benzyloxycarbonyl group.

As a protective group, CBZ masks certain reactive functional groups, preventing them from reacting with other reagents or substrates under specific reaction conditions. It is commonly used to protect amines involved in nucleophilic substitution reactions or to prevent undesired side reactions with other electrophilic species. The benzyloxycarbonyl group can be easily introduced using reagents such as benzyl chloroformate or benzyl carbamate, and removed afterward to regenerate the original compound.

CBZ has wide applications in organic synthesis, especially in the pharmaceutical industry, where it plays a crucial role in protecting reactive functional groups during the synthesis of complex organic molecules. Its widespread usage and versatility make it an essential tool for chemists working in various research fields.

Common Misspellings for CBZ


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