How Do You Spell CDK4?

Pronunciation: [sˌiːdˌiːkˈe͡ɪ fˈɔː] (IPA)

The spelling of "CDK4" may seem confusing at first glance, but it can be easily explained through the use of phonetic transcription. "CDK4" stands for "cyclin-dependent kinase 4," and the "C" is pronounced as /s/ and the "K" as /k/. The "D" is pronounced as /d/, and the "4" is pronounced as "four" or /fɔːr/. Therefore, the IPA phonetic transcription for "CDK4" would be /ˌsaɪk lɪn dɪˈpɛndənt ˈkaɪn eɪs ˈfɔr/.

CDK4 Meaning and Definition

  1. CDK4, also known as Cyclin-Dependent Kinase 4, is a protein-coding gene that is a member of the cyclin-dependent kinase family. CDK4 plays a crucial role in cell cycle progression and regulation, specifically during the G1 phase. This kinase is responsible for promoting cell division and proliferation by phosphorylating various target proteins involved in cell cycle control.

    CDK4 acts in association with its regulatory subunit, Cyclin D1, forming a complex that phosphorylates and inactivates the retinoblastoma protein (RB1), allowing the progression of the cell cycle. The activation of CDK4 is tightly regulated and relies on the presence of specific cyclin proteins, as well as the presence of certain growth factors and signaling pathways.

    Mutations or dysregulation of CDK4 are associated with a variety of diseases, including various forms of cancer. In certain cancers, such as melanoma, specific mutations in the CDK4 gene result in its overactivation, leading to uncontrolled cell division and tumor growth. Therefore, CDK4 has become an important target for therapeutic interventions, particularly in the field of cancer research.

    In summary, CDK4 is a kinase protein that plays a crucial role in cell cycle progression, promoting cell division and proliferation. Its dysregulation is implicated in the development of various diseases, particularly cancer, and targeting CDK4 has emerged as a potential strategy in cancer treatment.

Common Misspellings for CDK4

  • cdik4
  • cdki4
  • cdk34
  • cdk43
  • cdke4
  • cdk4e
  • cdkr4
  • cdk4r
  • cdk54
  • cdk45
  • ckd4
  • cdkk4
  • cdk44
  • sDK4
  • gDK4
  • aDK4
  • bDK4
  • CtK4
  • c dk4
  • cd k4

Etymology of CDK4

The acronym CDK4 stands for "Cyclin Dependent Kinase 4".

- Cyclin: It is derived from the word "cycle" and refers to a group of regulatory proteins that control the progression of the cell cycle.

- Dependent: Means that CDK4 relies on the interaction with cyclins to be active and carry out its functions.

- Kinase: Refers to an enzyme that catalyzes the transfer of a phosphate group from ATP to a protein, often involved in the regulation of various cellular processes.

Therefore, CDK4 is named as such because it is a cyclin-dependent kinase that specifically functions as the fourth member of the cyclin-dependent kinase family.

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