How Do You Spell CELL DEGRANULATION?

Pronunciation: [sˈɛl dɪɡɹˌanjʊlˈe͡ɪʃən] (IPA)

Cell degranulation is the process by which cells release their granules or contents. The correct spelling of this term is /sɛl ˌdiːɡrænjuˈleɪʃən/. The first syllable, /sɛl/, is spelled with a C because it represents the root word "cell." The second syllable, /diːɡræn/, is spelled with a G because it comes from the word "granule." Finally, the last syllable, /juˈleɪʃən/, represents the action of releasing the granules and is spelled using a combination of the letters J and U.

CELL DEGRANULATION Meaning and Definition

  1. Cell degranulation is a physiological process in which specialized storage structures within cells, known as granules, release their contents into the surrounding extracellular environment. This process is primarily observed in immune cells, such as mast cells, eosinophils, and basophils, as well as platelets. Granules contain various biologically active molecules, including histamine, cytokines, proteases, and growth factors.

    Cell degranulation is an essential mechanism in immune responses, as it plays a crucial role in the body's defense against pathogens and in inflammatory reactions. Upon stimulation by an appropriate trigger, such as an immune response or tissue injury, the cell's granules are rapidly mobilized and fuse with the cell membrane, thereby releasing their contents. This release can occur through a process known as exocytosis, where the granule membrane fuses with the plasma membrane, or by the rupture of the granule membrane.

    The released substances exert diverse effects on the surrounding cells and tissues. For example, histamine released by mast cells can induce vasodilation and increase vascular permeability, leading to the characteristic symptoms of allergic reactions. Additionally, cytokines released during degranulation can attract and activate other immune cells, amplifying immune responses. Proteases can degrade extracellular matrix components, enabling immune cells to migrate to the site of infection or inflammation.

    Overall, cell degranulation is a fundamental process in immune and inflammatory responses, facilitating the communication and coordination of immune cells and effector molecules to protect the body against foreign invaders and maintain tissue homeostasis.

Common Misspellings for CELL DEGRANULATION

  • xell degranulation
  • vell degranulation
  • fell degranulation
  • dell degranulation
  • cwll degranulation
  • csll degranulation
  • cdll degranulation
  • crll degranulation
  • c4ll degranulation
  • c3ll degranulation
  • cekl degranulation
  • cepl degranulation
  • ceol degranulation
  • celk degranulation
  • celp degranulation
  • celo degranulation
  • cell segranulation
  • cell xegranulation
  • cell cegranulation
  • cell fegranulation

Etymology of CELL DEGRANULATION

The term "cell degranulation" is composed of two parts: "cell" and "degranulation".

1. Cell: The word "cell" is derived from the Latin word "cella", meaning "small room" or "chamber". It originated in the late 17th century to refer to the smallest structural and functional unit of living organisms. The word "cell" has been used to describe various microstructures in different fields of study, and in the context of "cell degranulation", it refers to a specialized type of cell.

2. Degranulation: The word "degranulation" is derived from the prefix "de-" (meaning "undo" or "remove") and "granule". "Granule" comes from the Latin word "granulum", meaning "small grain" or "seed".

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