How Do You Spell COOLEY'S ANEMIA?

Pronunciation: [kˈuːlɪz ɐnˈiːmi͡ə] (IPA)

Cooley's anemia, also known as thalassemia major, is a genetic blood disorder that affects the production of hemoglobin. It is named after Thomas Cooley who was the first to describe the disease. The spelling of "Cooley's" is pronounced /ˈkuːli/ in IPA phonetic transcription. The "oo" sound is represented by the IPA symbol /u/ and the "l" sound is represented by /l/. Anemia, which refers to a deficiency of red blood cells, is pronounced /əˈniːmiə/ with the stressed syllables being represented by /ni/ and /mi/.

COOLEY'S ANEMIA Meaning and Definition

  1. Cooley's anemia, also known as beta-thalassemia major, is a genetic blood disorder characterized by an abnormality in the production of hemoglobin, the protein responsible for carrying oxygen in red blood cells. It is an inherited condition caused by mutations in both beta globin genes, which results in a severe deficiency of beta globin chains necessary for the formation of hemoglobin.

    Individuals with Cooley's anemia exhibit a range of symptoms including fatigue, pale skin, shortness of breath, poor growth, enlargement of the spleen and liver, and frequent infections. The most severe cases of Cooley's anemia may require blood transfusions for the affected individual's entire lifespan to mitigate the symptoms and maintain adequate oxygen levels in the body.

    Without proper treatment, Cooley's anemia can lead to serious complications such as iron overload, due to the body's inability to properly process the excess iron received through transfusions. Iron accumulation can cause damage to vital organs like the heart, liver, and endocrine system. Individuals with Cooley's anemia may also develop skeletal abnormalities such as bone deformities and an enlarged head.

    The management of Cooley's anemia involves regular blood transfusions to maintain normal hemoglobin levels, as well as treatments to remove excess iron from the body through chelation therapy. Additionally, individuals may undergo bone marrow transplantation to provide healthy bone marrow cells capable of producing normal hemoglobin.

    Cooley's anemia is a chronic condition that typically requires lifelong medical intervention to manage symptoms and optimize quality of life.

Common Misspellings for COOLEY'S ANEMIA

  • xooley's anemia
  • vooley's anemia
  • fooley's anemia
  • dooley's anemia
  • cioley's anemia
  • ckoley's anemia
  • cloley's anemia
  • cpoley's anemia
  • c0oley's anemia
  • c9oley's anemia
  • coiley's anemia
  • cokley's anemia
  • colley's anemia
  • copley's anemia
  • co0ley's anemia
  • co9ley's anemia
  • cookey's anemia
  • coopey's anemia
  • coooey's anemia

Etymology of COOLEY'S ANEMIA

The word "Cooley's Anemia" is named after the American pediatrician Dr. Thomas Benton Cooley. Cooley first described the condition in 1925 while working at Children's Hospital in Boston. He called it "Cooley's Anemia" in honor of his contribution to understanding and diagnosing this particular form of severe genetic anemia.

Plural form of COOLEY'S ANEMIA is COOLEY'S ANEMIAS

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