COOLEY'S ANAEMIA Meaning and Definition
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Cooley's Anaemia, also known as beta-thalassemia major or thalassemia major, is a rare genetic blood disorder characterized by the inability to produce sufficient functional hemoglobin in the body. This condition is named after the American pediatrician Thomas Cooley who first described it in the early 20th century.
People with Cooley's Anaemia inherit a specific gene mutation that affects the production of hemoglobin, the protein responsible for delivering oxygen to tissues throughout the body. Due to this mutation, the body produces insufficient or no beta-globin chains, leading to the abnormal formation of red blood cells. As a result, affected individuals suffer from severe anemia, as the lack of functional hemoglobin impairs oxygen transport.
Symptoms of Cooley's Anaemia typically manifest within the first year of life and may include pale skin, fatigue, slow growth, delayed puberty, bone deformities, enlarged spleen, and yellowing of the skin and eyes (jaundice). Without proper treatment, the condition can cause life-threatening complications, such as heart failure, organ damage, and increased susceptibility to infections.
Management of Cooley's Anaemia involves regular blood transfusions to alleviate anemia and provide adequate oxygen supply, as well as iron chelation therapy to prevent iron overload from frequent transfusions. Additionally, some patients may require bone marrow transplants, which can potentially cure the disorder. Early detection through genetic testing and counseling is crucial for families with a history of Cooley's Anaemia to make informed decisions about family planning options.
Common Misspellings for COOLEY'S ANAEMIA
- xooley's anaemia
- vooley's anaemia
- fooley's anaemia
- dooley's anaemia
- cioley's anaemia
- ckoley's anaemia
- cloley's anaemia
- cpoley's anaemia
- c0oley's anaemia
- c9oley's anaemia
- coiley's anaemia
- cokley's anaemia
- colley's anaemia
- copley's anaemia
- co0ley's anaemia
- co9ley's anaemia
- cookey's anaemia
- coopey's anaemia
Etymology of COOLEY'S ANAEMIA
The word "Cooley's Anaemia" originates from the last name of the American physician who first described the condition, Dr. Thomas B. Cooley. He identified and published a comprehensive report on the disease in 1925 in the United States, which is now known as thalassemia major. As a tribute to his significant contributions to the understanding and classification of the disease, the condition was named after him by the medical community. Thus, the etymology of "Cooley's Anaemia" is derived from Dr. Thomas B. Cooley's name.
Plural form of COOLEY'S ANAEMIA is COOLEY'S ANAEMIAS
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