CROSPOVIDONE Meaning and
Definition
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Crospovidone, also known by its chemical name polyvinylpyrrolidone crosslinked, is a widely used pharmaceutical excipient. It is a white, free-flowing powder that possesses excellent binding and disintegrating properties. Crospovidone is commonly employed as a disintegrant, which aids in the rapid breakdown of tablets or capsules into smaller particles when they come in contact with the fluids in the gastrointestinal tract. This property makes it highly valuable in drug formulations where fast dissolution and release of the active ingredient are desired.
With its high molecular weight and extensive crosslinking, crospovidone exhibits high water absorbing capacity, allowing it to rapidly swell when exposed to moisture. This property is advantageous for promoting disintegration as it increases the surface area available for drug dissolution. Additionally, crospovidone demonstrates excellent compressibility, making it ideal for tablet manufacturing processes, where it helps to form solid, hard tablets from powdered ingredients.
Crospovidone is considered safe for human consumption, as it is insoluble in water and does not get absorbed into the bloodstream. It possesses a broad range of applications in the pharmaceutical industry, primarily as a disintegrant and binder, but also as a suspending agent and stabilizer for various formulations. Furthermore, it is compatible with a wide range of active pharmaceutical ingredients, enabling its use in a diverse range of drug formulations.
In summary, crospovidone is a versatile pharmaceutical excipient used for its disintegrating and binding properties in the manufacturing of tablets and capsules.
Common Misspellings for CROSPOVIDONE
- xrospovidone
- vrospovidone
- frospovidone
- drospovidone
- ceospovidone
- cdospovidone
- cfospovidone
- ctospovidone
- c5ospovidone
- c4ospovidone
- crispovidone
- crkspovidone
- crlspovidone
- crpspovidone
- cr0spovidone
- cr9spovidone
- croapovidone
- crozpovidone
- croxpovidone
- crodpovidone
Etymology of CROSPOVIDONE
The word "Crospovidone" is a combination of two parts: "Cros-" and "povidone".
The "Cros-" part of the word is not of clear etymology as it seems to be a proprietary term coined by the company that first developed the substance. It is associated with the parent company's initials, and the exact origin or meaning of "Cros-" is not readily apparent.
The second part of the word, "povidone", has a more transparent etymology. It is derived from two words: "polyvinyl" and "pyrrolidone".
"Polyvinyl" refers to a type of synthetic resin made from the polymerization of vinyl chloride. It is commonly used to produce various plastic materials.
"Pyrrolidone" is a compound derived from pyrrole, an organic compound commonly found in certain plants, coal tar, or can be synthesized.
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