CYCLIN E Meaning and
Definition
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Cyclin E is a protein that plays a crucial role in cell cycle regulation. It is a member of the cyclin family, proteins that bind to cyclin-dependent kinases (CDKs) to regulate the progression through different phases of the cell cycle. Cyclin E specifically interacts with the CDK2 protein, forming a complex that promotes the transition from G1 phase to S phase of the cell cycle.
During the G1 phase, cyclin E expression increases, leading to the formation of the cyclin E-CDK2 complex. This complex subsequently phosphorylates target proteins that are involved in DNA replication and cellular proliferation, initiating the entry into S phase. Thus, Cyclin E is responsible for regulating the progression of cells from the resting phase of the cell cycle to the DNA synthesis phase.
The expression and activity of Cyclin E are tightly controlled, ensuring proper cell cycle progression and preventing uncontrolled cell division. Dysregulation or overexpression of cyclin E has been associated with various types of cancer. High levels of Cyclin E have been found in tumors, indicating its involvement in promoting abnormal cell growth and division.
Overall, Cyclin E is a crucial protein that regulates the cell cycle by promoting the transition from G1 phase to S phase. Its dysregulation can have important implications for cell growth and division, leading to the development of cancerous cells.
Common Misspellings for CYCLIN E
- xyclin e
- vyclin e
- fyclin e
- dyclin e
- ctclin e
- cgclin e
- chclin e
- cuclin e
- c7clin e
- c6clin e
- cyxlin e
- cyvlin e
- cyflin e
- cydlin e
- cyckin e
- cycpin e
- cycoin e
- cyclun e
- cycljn e
- cyclkn e
Etymology of CYCLIN E
The word "Cyclin E" is primarily derived from two sources: the word "cyclin" and the letter "E".
The term "cyclin" comes from the Greek word "kyklos", meaning "cycle" or "circle". Cyclin is a type of protein that plays a crucial role in the regulation of the cell cycle in eukaryotic cells. It was named cyclin because its levels fluctuate in a cyclical manner throughout the cell cycle.
The letter "E" in "Cyclin E" refers to a specific subtype or isoform of the cyclin protein family. Cyclins are typically denoted by letters to distinguish them from one another and indicate their specific functions and roles within the cell cycle. In this case, "E" represents Cyclin E, one of the cyclins that regulates the transition from G1 phase to S phase during the cell cycle.
Similar spelling words for CYCLIN E
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