DEREPLICATION Meaning and
Definition
-
Dereplication is a term commonly used in the field of natural product chemistry and drug discovery. It refers to a process of eliminating and identifying known or previously reported compounds from a sample or mixture of compounds. This process is important to avoid redundancy and duplication in the identification and characterization of novel natural products or drug candidates.
In practice, dereplication involves the use of various analytical techniques, such as chromatography, spectroscopy, and mass spectrometry, to compare the chemical fingerprints of the compounds in the sample with those of known compounds present in databases. By matching these fingerprints, dereplication enables researchers to rapidly identify known compounds and exclude them from further analysis.
Dereplication plays a crucial role in natural product exploration since it helps researchers to focus their efforts on discovering new bioactive compounds and chemical entities that may have potential pharmaceutical or medical applications. By identifying known compounds early on, researchers can prevent unnecessary duplication of work and resources. It also aids in streamlining the process of identifying and characterizing new compounds, as the focus is primarily on exploring uncharted chemical space.
Overall, dereplication is a vital tool in natural product chemistry and drug discovery that allows researchers to efficiently prioritize, streamline, and accelerate the discovery of novel compounds and potential drugs.
Common Misspellings for DEREPLICATION
- sereplication
- xereplication
- cereplication
- fereplication
- rereplication
- eereplication
- dwreplication
- dsreplication
- ddreplication
- drreplication
- d4replication
- d3replication
- deeeplication
- dedeplication
- defeplication
- deteplication
- de5eplication
- de4eplication
- derwplication
- dersplication
Etymology of DEREPLICATION
The word "dereplication" is derived from the combination of two words: "de-" and "replication".
1. "De-" is a Latin prefix that means "off", "down", or "remove". It is commonly used to indicate a reversal or a negative action.
2. "Replication" comes from the Latin word "replicatio" which means "a folding back, a doubling". In a scientific context, it refers to the process of making multiple copies or reproducing something, particularly in relation to DNA or genetic material.
So, when combined, "dereplication" essentially means the removal or elimination of replication, often used in the context of isolating or identifying novel compounds or microorganisms from natural sources without duplicating existing or known ones.
Infographic
Add the infographic to your website:
