DESMETHYLLOXAPINE Meaning and
Definition
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Desmethylloxapine is a chemical compound that belongs to the class of tricyclic antidepressants (TCAs). This compound is an active metabolite of the medication loxapine. Desmethylloxapine is formed when the liver breaks down loxapine into its metabolites.
As a TCA, desmethylloxapine works by inhibiting the reuptake of neurotransmitters such as norepinephrine and serotonin in the brain. By preventing the reuptake of these neurotransmitters, it increases their concentration in the synaptic cleft, enhancing their effects on the postsynaptic receptors. This mechanism leads to an improvement in mood and relief from symptoms of depression.
Desmethylloxapine is primarily used in the treatment of depressive disorders, including major depressive disorder (MDD). It can also be employed as an adjunct treatment for other conditions such as anxiety disorders, panic disorder, and obsessive-compulsive disorder (OCD).
While desmethylloxapine is chemically similar to loxapine, it possesses unique pharmacological properties. It has a longer half-life and lower potency compared to its parent compound. Thus, desmethylloxapine is considered an important metabolite that contributes to the overall therapeutic effects of loxapine.
It is worth noting that the use of desmethylloxapine should be carefully monitored by healthcare professionals due to potential side effects, including drowsiness, dizziness, dry mouth, constipation, and blurred vision. Additionally, it may interact with other medications, so it is crucial to consult with a healthcare provider before starting or adjusting the dose of desmethylloxapine.
Common Misspellings for DESMETHYLLOXAPINE
- sesmethylloxapine
- xesmethylloxapine
- cesmethylloxapine
- fesmethylloxapine
- resmethylloxapine
- eesmethylloxapine
- dwsmethylloxapine
- dssmethylloxapine
- ddsmethylloxapine
- drsmethylloxapine
- d4smethylloxapine
- d3smethylloxapine
- deamethylloxapine
- dezmethylloxapine
- dexmethylloxapine
- dedmethylloxapine
- deemethylloxapine
- dewmethylloxapine
- desnethylloxapine
- deskethylloxapine
Etymology of DESMETHYLLOXAPINE
The word "Desmethylloxapine" consists of two main components: "desmethyl" and "loxapine".
1. "Desmethyl" is derived from the Greek prefix "des" meaning "removal" or "absence" and "methyl", which refers to a molecule consisting of one carbon atom attached to three hydrogen atoms (CH3). In this context, "desmethyl" indicates the removal of a methyl group from a compound.
2. "Loxapine" is a pharmaceutical compound used as an antipsychotic medication. The origin of "loxapine" is not entirely clear, but it is believed to be derived from the combination of "lox-" and "-pine".
- "Lox-" may come from the name of an American pharmaceutical company, Lederle Laboratories. However, this connection is speculative and not widely accepted.
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