DICOUMAROL Meaning and
Definition
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Dicoumarol is a chemical compound that belongs to the class of coumarin derivatives. It is derived from the hydrolysis of coumarin glycosides, which are natural plant substances found in diverse plant species. Dicoumarol is widely known for its anticoagulant properties, as it inhibits the synthesis of blood clotting factors, thereby preventing or delaying blood clot formation.
In terms of its chemical structure, dicoumarol consists of two coumarin rings connected by a central chain of hydrocarbons. This molecular configuration allows dicoumarol to interfere with the activities of vitamin K, a vital component in the production of clotting factors. By competitively inhibiting vitamin K epoxide reductase, dicoumarol leads to a deficiency of activated vitamin K, which is essential for the proper functioning of clotting factors II, VII, IX, and X. Consequently, the absence of these factors results in an increased clotting time and a decreased capacity for blood to coagulate.
Dicoumarol gained significant attention in the medical field due to its use as a precursor for the development of oral anticoagulant drugs, including warfarin. These medications are commonly prescribed for individuals at risk of thromboembolic disorders, such as deep vein thrombosis or atrial fibrillation. However, caution must be exercised with dicoumarol and its derivatives, as their anticoagulant properties can lead to a higher risk of bleeding complications. It is imperative for individuals taking such medications to be closely monitored by healthcare professionals and maintain regular blood tests to ensure appropriate dosage and safety.
Common Misspellings for DICOUMAROL
- sicoumarol
- xicoumarol
- cicoumarol
- ficoumarol
- ricoumarol
- eicoumarol
- ducoumarol
- djcoumarol
- dkcoumarol
- docoumarol
- d9coumarol
- d8coumarol
- dixoumarol
- divoumarol
- difoumarol
- didoumarol
- diciumarol
- dickumarol
- diclumarol
Etymology of DICOUMAROL
The word "dicoumarol" is derived from the chemical compound it refers to, courmarin, and the prefix "di-".
Courmarin, also spelled coumarin, is a fragrant organic compound that is naturally found in plants such as tonka beans, sweet woodruff, and cassia cinnamon. The term "courmarin" originates from the French word "coumarou", which refers to the tonka bean tree.
The prefix "di-" in "dicoumarol" indicates that the compound is a derivative or has two courmarin molecules. Dicoumarol is an anticoagulant compound that was discovered in the 1940s when it was found to cause hemorrhages in cattle consuming spoiled sweet clover hay.
Similar spelling word for DICOUMAROL
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