DLX3 Meaning and
Definition
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DLX3 is a gene that encodes a protein involved in the growth and development of various tissues in organisms, particularly in the formation of teeth and bone. The term DLX3 stands for Distal-less homeobox 3, which is derived from the classification of homeobox genes that function in the development of body structures in multicellular organisms.
DLX3 belongs to the DLX family, a group of genes that are important in embryonic development and cellular differentiation. It contains a DNA-binding region known as the homeodomain, which enables it to bind to specific DNA sequences and regulate the expression of other genes. DLX3 is primarily expressed in specialized cells of the skeletal system, such as those found in teeth and craniofacial structures.
Mutations in the DLX3 gene have been linked to a genetic disorder known as tricho-dento-osseous (TDO) syndrome. Individuals with TDO syndrome exhibit abnormal hair, teeth, and bones. DLX3 mutations can affect the normal development and maintenance of these tissues, leading to anomalies in their structure and function.
Research on DLX3 continues to shed light on its precise role in cellular pathways and tissue development. Understanding the mechanisms by which DLX3 operates may have implications for treatments and interventions related to dental and skeletal disorders.
Common Misspellings for DLX3
- xlx3
- flx3
- rlx3
- elx3
- dlx2
- dlx4
- sdlx3
- dslx3
- xdlx3
- dxlx3
- cdlx3
- dclx3
- fdlx3
- dflx3
- rdlx3
- drlx3
- edlx3
- delx3
- dklx3
- dlkx3
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