DYNORPHINS Meaning and
Definition
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Dynorphins are a group of endogenous opioid peptides that belong to the opioid peptide family. They are important neurotransmitters found primarily in the central nervous system, with high concentrations in regions such as the hypothalamus and spinal cord. Dynorphins are derived from the precursor protein prodynorphin, which is encoded by the PDYN gene.
Known for their potent analgesic properties, dynorphins act upon opioid receptors in the brain and spinal cord to modulate pain perception and transmission. They play a critical role in regulating various physiological processes such as mood, reward, stress response, and addiction. Additionally, dynorphins are involved in the regulation of appetite, immune function, and cardiovascular function.
The release of dynorphins is often stimulated during physical or emotional stress, as well as in response to injuries. These peptides bind to kappa opioid receptors, one of the three major types of opioid receptors in the body. Activation of these receptors by dynorphins leads to inhibition of neurotransmitter release, ultimately resulting in pain relief.
Despite their analgesic effects, excessive dynorphin release has been associated with negative consequences. It has been suggested that dynorphins may contribute to the development of chronic pain conditions and neurological disorders such as depression and anxiety. Consequently, the study of dynorphins and their interactions with opioid receptors continues to be an area of ongoing research in the field of neuroscience and pharmacology.
Common Misspellings for DYNORPHINS
- synorphins
- xynorphins
- cynorphins
- fynorphins
- rynorphins
- eynorphins
- dtnorphins
- dgnorphins
- dhnorphins
- dunorphins
- d7norphins
- d6norphins
- dyborphins
- dymorphins
- dyjorphins
- dyhorphins
- dynirphins
- dynkrphins
- dynlrphins
- dynprphins
Etymology of DYNORPHINS
The word "dynorphins" has a Greek origin. It is derived from two Greek words: "dynami" meaning "power" or "force", and "morphe" meaning "form" or "shape". When combined, the term dynorphin can be translated to mean "powerful form" or "powerful shape". Dynorphins are a type of opioid peptide that play a role in various physiological functions, especially in the regulation of pain and mood.
