EGMM Meaning and
Definition
-
eGMM, also known as the eigengene-based Gaussian mixture model, is a statistical method primarily used in bioinformatics and genetics to identify and classify patterns of gene expression data. It is a technique developed to analyze high-dimensional gene expression data obtained from microarray experiments or RNA sequencing.
The term "eGMM" refers to the integration of two important concepts: eigengene analysis and Gaussian mixture modeling. The eigengene analysis is a method for summarizing gene expression data by identifying the principal components or eigenvectors of a dataset. These eigenvectors capture the variation in gene expression across samples and are used to construct representative gene expression profiles called eigengenes.
Gaussian mixture modeling is a statistical technique that assumes the underlying probability distribution of a dataset is a mixture of several Gaussian distributions. By applying this technique to eigengenes, eGMM aims to uncover distinct subgroups or clusters within the gene expression data. In other words, it helps in identifying groups of genes that exhibit similar expression patterns across different experimental conditions or samples.
The eGMM method provides a framework to overcome the limitations of traditional clustering algorithms by combining the dimensionality reduction capabilities of eigengene analysis with the flexibility of Gaussian mixture modeling. It allows researchers to identify and characterize different subtypes or classes within complex gene expression datasets, enabling better understanding of biological processes and potentially leading to novel discoveries related to disease mechanisms, drug responses, and biomarker identification.
Common Misspellings for EGMM
- 4gmm
- 3gmm
- wegmm
- ewgmm
- 4egmm
- e4gmm
- 3egmm
- e3gmm
- ehgmm
- etgmm
- egtmm
- egnmm
- egjmm
- egmjm
- egmmk
- egmmj
- e gmm
- eg mm
- egm m
Infographic
Add the infographic to your website:
