FAMILIAL EXOSTOSIS Meaning and
Definition
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Familial exostosis, also known as hereditary multiple exostoses (HME), is a genetic disorder characterized by the presence of multiple benign bone growths called exostoses or osteochondromas. These growths typically occur in the long bones of the body, such as the arms and legs, as well as in the flat bones, such as the pelvis and shoulder blades.
Individuals affected by familial exostosis usually develop multiple exostoses during childhood or adolescence, and the condition can vary in severity from person to person. The size and number of exostoses can increase over time, potentially leading to various complications, such as impaired movement, unequal limb length, joint pain, nerve compression, or skeletal deformities.
Familial exostosis is an inherited condition caused by mutations in specific genes that are involved in the regulation of bone growth. The genetic transmission pattern is most commonly autosomal dominant, meaning that an affected individual has a 50% chance of passing the condition on to each of their children.
Diagnosis of familial exostosis is typically based on the presence of physical symptoms, such as visible exostoses on X-rays, along with a detailed family history. Genetic testing can also be conducted to identify the specific gene mutations responsible for the condition.
Treatment for familial exostosis aims to address any symptoms or complications that arise from the presence of exostoses. This may include surgical removal of problematic growths, physical therapy, orthopedic interventions, or pain management strategies. Regular monitoring is essential to assess the progression of the condition and ensure appropriate management.
Common Misspellings for FAMILIAL EXOSTOSIS
- damilial exostosis
- camilial exostosis
- vamilial exostosis
- gamilial exostosis
- tamilial exostosis
- ramilial exostosis
- fzmilial exostosis
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- famulial exostosis
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- famikial exostosis
Etymology of FAMILIAL EXOSTOSIS
The term "Familial Exostosis" has its etymology rooted in Latin and Greek.
The word "Familial" is derived from the Latin word "familiālis", which means "relating to a household" or "pertaining to a family". It is formed from the Latin noun "famīlia" meaning "family" and the suffix "-alis" denoting "relating to" or "belonging to".
The word "Exostosis" has its origins in the Greek language. It is formed from the Greek prefix "ek-" meaning "out of" or "away from", and the Greek noun "ostoun" which translates to "bone". The suffix "-osis" is a Greek suffix that indicates a condition or process.
