How Do You Spell FUSION GENE?

Pronunciation: [fjˈuːʒən d͡ʒˈiːn] (IPA)

The term "fusion gene" is commonly used in genetics to describe a genetic aberration where two or more genes join together to create a single hybrid gene. The spelling of this term is [ˈfjuːʒən dʒiːn] in IPA phonetic transcription. The term is spelled with the letter 'f' instead of 'ph' and 's' instead of 'c' to represent the sound of the consonants more accurately. The 'u' in fusion makes a long 'u' sound, while 'g' in gene makes a hard 'j' sound, as in 'jump'.

FUSION GENE Meaning and Definition

1. A fusion gene refers to a type of genetic alteration that occurs when two separate genes, coming from different regions of the genome, become joined together in a single gene. This fusion results from a recombination event between two different chromosomes or within the same chromosome. As a consequence, the new fusion gene contains sequences from both original genes, resulting in a hybrid gene with a different structure and functionality.

   The fusion gene formation can arise due to various mechanisms, including chromosomal translocations, inversions, or gene fusions caused by retrotransposition. These genetic rearrangements can occur spontaneously or through exposure to mutagenic agents such as radiation or certain chemicals. Fusion genes can also arise as a result of errors in DNA repair processes.

   The fusion gene can have significant impacts on cellular function and can potentially lead to the development of certain diseases, including cancer. It is a recurrent event observed in several types of cancers, where it drives abnormal cell growth and division. Fusion genes may result in the production of novel proteins with altered functions, loss of regulatory elements, or disruption of normal gene expression. These changes can contribute to the initiation and progression of cancer by promoting uncontrolled cell proliferation or inhibiting apoptosis.

   Fusion genes are actively studied in genetics and molecular biology research, aiming to better understand their roles in diseases and explore potential diagnostic, prognostic, and therapeutic applications.

Common Misspellings for FUSION GENE

• dusion gene
• cusion gene
• vusion gene
• gusion gene
• tusion gene
• rusion gene
• fysion gene
• fhsion gene
• fjsion gene
• fision gene
• f8sion gene
• f7sion gene
• fuaion gene
• fuzion gene
• fuxion gene
• fudion gene
• fueion gene
• fuwion gene
• fusuon gene
• fusjon gene

Etymology of FUSION GENE

The word "fusion gene" is derived from the combination of two terms: "fusion" and "gene".

The term "fusion" originates from the Latin word "fusio", which means "a melting or blending together". It is commonly used in the context of combining two or more separate entities into one. In the case of a fusion gene, the term refers to the blending or merging of two different genes, resulting in a new hybrid gene.

The word "gene" comes from the Greek word "genos", meaning "origin" or "birth". It was first coined by Danish botanist and geneticist Wilhelm Johannsen in the early 20th century to describe the fundamental unit of heredity, responsible for the transmission of traits from parents to offspring.

Plural form of FUSION GENE is FUSION GENES