How Do You Spell GUANYLYL IMIDODIPHOSPHATE?

Pronunciation: [ɡwˈɑːnɪlˌɪl ɪmˈɪdədˌɪfəsfˌe͡ɪt] (IPA)

The word "Guanylyl Imidodiphosphate" is a mouthful. The phonetic transcription of this word is [ɡwɑnəˌlɪl ɪˌmɪdoʊdaɪˈfɑsfeɪt], which may help you understand its spelling. The "G" is pronounced as "gway," as in "guitar." "U" sounds like "wuh," as in "wanted." "Y" sounds like "ee," as in "meet," and "L" sounds like "lul." "I" is pronounced like "ih," as in "it." "D" is "duh," and "P" is "puh." Remember, practice makes perfect when it comes to pronouncing complicated words like this.

GUANYLYL IMIDODIPHOSPHATE Meaning and Definition

  1. Guanylyl Imidodiphosphate, often abbreviated as GppNHp, is a chemical compound used in molecular biology and biochemistry research. It is an analog of guanosine triphosphate (GTP) and functions as a non-hydrolyzable analog of GTP.

    GppNHp is composed of a guanine base, a ribose sugar, and three phosphate groups. Compared to GTP, it contains an imidodiphosphate group, which replaces one of the terminal phosphate groups. This modification prevents enzymatic hydrolysis by phosphatases, allowing GppNHp to be used for studies where GTPase activity needs to be inhibited or its effects need to be prolonged.

    In biological systems, GTP is essential for various cellular processes, including protein synthesis, signal transduction, and intracellular transportation. By using GppNHp, researchers can stabilize GTP-interacting proteins or inhibit GTPase enzymes that regulate GTP hydrolysis. This analog has been particularly valuable in studying GTP-binding proteins, such as G-proteins, which play essential roles in cellular signal transduction.

    Aside from its applications in research, GppNHp has also been utilized in pharmaceutical studies to develop potential drugs that can target GTP-binding proteins and interfere with their functions.

    In summary, Guanylyl Imidodiphosphate is a non-hydrolyzable analog of GTP that serves as a valuable tool in molecular biology and biochemistry research. Its imidodiphosphate modification confers stability and the ability to inhibit GTPase activity, making it crucial for investigating GTP-binding proteins and their involvement in cellular processes.

Common Misspellings for GUANYLYL IMIDODIPHOSPHATE

  • fuanylyl imidodiphosphate
  • vuanylyl imidodiphosphate
  • buanylyl imidodiphosphate
  • huanylyl imidodiphosphate
  • yuanylyl imidodiphosphate
  • tuanylyl imidodiphosphate
  • gyanylyl imidodiphosphate
  • ghanylyl imidodiphosphate
  • gjanylyl imidodiphosphate
  • gianylyl imidodiphosphate
  • g8anylyl imidodiphosphate
  • g7anylyl imidodiphosphate
  • guznylyl imidodiphosphate
  • gusnylyl imidodiphosphate
  • guwnylyl imidodiphosphate
  • guqnylyl imidodiphosphate
  • guabylyl imidodiphosphate
  • guamylyl imidodiphosphate
  • guajylyl imidodiphosphate
  • guahylyl imidodiphosphate

Etymology of GUANYLYL IMIDODIPHOSPHATE

The word "Guanylyl Imidodiphosphate" is a combined term derived from the chemical compounds it consists of.

- "Guanylyl" refers to the guanine nucleotide derivative "guanosine monophosphate" (GMP), which is formed by the enzyme guanylate kinase. It is derived from the molecule called "guanine" found in DNA and RNA.

- "Imidodiphosphate" is composed of two parts:

- "Imido" is derived from "imidazole", which is a type of organic compound.

- "Diphosphate" refers to a pyrophosphate ion, which contains two phosphate groups (PO4-).

When combined, "Guanylyl Imidodiphosphate" describes a specific molecule consisting of a guanosine monophosphate derivative and an imidazole compound, along with two phosphate groups.