How Do You Spell IL1B?

Pronunciation: [ˈɪl wˈɒn bˈiː] (IPA)

The spelling of "IL1B" is derived from the full name of the gene: Interleukin-1 beta. Interleukins are signaling molecules involved in the immune response to injury and infection. "IL1B" is a shorthand way to represent the gene in scientific literature and medical writing. The spelling of "IL1B" in IPA phonetic transcription is /ɪntəˈluːkɪn wʌn biː/. This pronunciation represents the individual letters and numbers used to represent each component of the gene abbreviation.

IL1B Meaning and Definition

1. IL1B, also known as Interleukin 1 beta, is a protein that belongs to the interleukin-1 family of cytokines. It is primarily produced by immune cells such as monocytes, macrophages, and dendritic cells, as well as non-immune cells including epithelial and endothelial cells, fibroblasts, and adipocytes. IL1B is a pro-inflammatory cytokine that plays a key role in the regulation of the immune response and inflammation.

   IL1B is synthesized as a biologically inactive precursor, pro-IL1B, which requires proteolytic cleavage by the enzyme caspase-1 to produce the active form of the protein. Once activated, IL1B acts on various target cells by binding to the interleukin-1 receptor (IL-1R) on their surface. This interaction triggers a signaling cascade that leads to the activation of genes involved in inflammation, immune cell adhesion, and tissue repair.

   IL1B is involved in a wide range of physiological and pathological processes. It has been implicated in the promotion of fever, induction of acute-phase proteins, activation of T and B lymphocytes, stimulation of bone resorption, and recruitment of neutrophils. Additionally, elevated levels of IL1B have been associated with chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease, and atherosclerosis.

   Due to its pivotal role in inflammation and immune responses, IL1B has been a target for therapeutic interventions. Various drugs and biologics have been developed to modulate IL1B activity and treat related disorders.

Common Misspellings for IL1B

• ilb1
• iil1b
• ill1b
• il11b
• yL1B
• aL1B
• mL1B
• hL1B
• Id1B
• Ih1B
• In1B
• Im1B
• IL9B
• IL5B
• IL3B
• IL0B
• IL1j
• IL1f

Etymology of IL1B

The term "IL1B" is an abbreviation for Interleukin-1 beta.

The word "interleukin" is derived from the Latin words "inter" meaning "between" and "leukos" meaning "white". This term was coined because interleukins were initially thought to be produced and act between white blood cells. Interleukins are a group of signaling molecules that play a role in various immune responses.

The number "1" in "IL1B" indicates the specific type or subtype of interleukin. There are multiple types of interleukins, each with distinct functions and effects on the immune system.

"IL1B" specifically refers to Interleukin-1 beta. The term "beta" denotes a particular isoform or variant of Interleukin-1.