How Do You Spell KAYSER-FLEISCHER RING?

Pronunciation: [kˈe͡ɪsəflˈɛʃə ɹˈɪŋ] (IPA)

The Kayser-Fleischer Ring is a medical term used to describe the brownish ring that appears around the cornea of people suffering from Wilson disease. The word "Kayser" is pronounced as ['kaɪzə] and "Fleischer" is pronounced as ['flaɪʃər]. The term is spelled as ["ˈkaɪzɚ ˈflaɪʃɚ ˌrɪŋ"] in IPA phonetic transcription. It is essential to spell medical terms correctly to ensure clarity and avoid misunderstandings. Accurate spelling of medical terminologies is necessary to communicate effectively with fellow healthcare professionals and patients alike.

KAYSER-FLEISCHER RING Meaning and Definition

  1. Kayser-Fleischer ring refers to a distinctive brownish-golden or greenish discoloration that can be observed at the periphery of the cornea of the eye. This condition is mainly associated with Wilson's disease, which is a rare inherited disorder characterized by the impaired metabolism and subsequent excessive accumulation of copper in various organs of the body. The Kayser-Fleischer ring is one of the clinical manifestations observed in individuals affected by this condition.

    The ring owes its name to two prominent physicians, Bernhard Kayser and Bruno Fleischer, who described and emphasized its significance in the diagnosis of Wilson's disease in the late 19th and early 20th centuries, respectively. The Kayser-Fleischer ring typically appears as a band-like formation near the edge of the cornea, with a width that can vary between a few millimeters to a centimeter. The color of the ring may range from light yellow to brown or green, depending on the extent of copper deposition.

    This corneal finding is a consequence of copper accumulation in the Descemet membrane and is generally considered a reliable indicator of Wilson's disease. The appearance of the Kayser-Fleischer ring is due to the deposition of copper in a layer of the cornea referred to as Descemet's membrane, resulting in the distinctive pigmentation. The detection of this ring during a thorough eye examination can aid in the diagnosis of Wilson's disease and prompt appropriate management, including referral for further evaluation and treatment to prevent further complications associated with copper overload in the body.

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Etymology of KAYSER-FLEISCHER RING

The term "Kayser-Fleischer ring" is named after two ophthalmologists, Dr. Bernhard Kayser and Dr. Bruno Fleischer, who independently described this characteristic brownish ring around the cornea in patients with a certain medical condition.

The Kayser-Fleischer ring is commonly observed in individuals with Wilson's disease, a genetic disorder that affects copper metabolism and leads to the accumulation of copper in various organs, including the liver and brain. Dr. Bernhard Kayser, a German ophthalmologist, first described this ring in 1902 after observing it in patients with liver diseases.

Dr. Bruno Fleischer, an Austrian ophthalmologist, later independently documented the same finding in 1903. Both doctors recognized the association of this ring with copper deposition in the cornea, which represented a significant diagnostic clue for Wilson's disease.