How Do You Spell KEARN SAYRE MITOCHONDRIAL CYTOPATHY?

Pronunciation: [kˈi͡ən sˈe͡ɪə mˌa͡ɪtəkˈɒndɹɪəl sa͡ɪtˈɒpəθɪ] (IPA)

The spelling of "Kearn Sayre Mitochondrial Cytopathy" can be explained using the International Phonetic Alphabet (IPA) phonetic transcription. The word begins with the "k" sound, followed by the "ɪə" diphthong in "Kearn." Next comes the "s" sound in "Sayre," followed by the "aɪ" diphthong. "Mitochondrial" contains the "m" sound followed by the "aɪ" diphthong again. Finally, "Cytopathy" has the "s" sound followed by "ɒ" and "θ" in rapid succession. Altogether, this word describes a severe genetic disorder affecting the central nervous system and eyesight.

KEARN SAYRE MITOCHONDRIAL CYTOPATHY Meaning and Definition

  1. Kearns-Sayre Mitochondrial Cytopathy, also known as Kearns-Sayre Syndrome (KSS), is a rare genetic disorder that affects the mitochondria, the tiny energy-producing structures within cells. This condition is primarily characterized by a group of symptoms that typically develop during childhood or adolescence.

    Kearns-Sayre Mitochondrial Cytopathy is caused by mutations in the DNA of mitochondria, which results in a deficiency of functional mitochondria within affected tissues. The specific genetic changes responsible for this disorder often involve deletions or rearrangements in the mitochondrial DNA.

    Individuals with Kearns-Sayre Mitochondrial Cytopathy may experience various symptoms, including progressive weakness of eye muscles, leading to involuntary eye movements (ophthalmoplegia) or drooping eyelids (ptosis). Other common features include heart problems like heart block, which affects the electrical signals controlling heart rhythm, and hearing loss caused by damage to the nerves involved in hearing (sensorineural deafness).

    In addition to the core symptoms, Kearns-Sayre Mitochondrial Cytopathy can also lead to various types of endocrine disorders, impaired coordination and balance (ataxia), muscle weakness, and difficulties swallowing (dysphagia). The severity of the condition can vary widely among affected individuals, with some experiencing mild symptoms and others facing more severe impairment.

    Currently, there is no cure for Kearns-Sayre Mitochondrial Cytopathy, and treatment options primarily focus on managing the symptoms. This may include corrective eyewear, hearing aids, medication to manage heart abnormalities, and physical therapy to improve muscle strength and coordination. Genetic counseling is also essential for affected individuals and their families to understand the inheritance pattern and risks of passing on the condition to future generations.

Common Misspellings for KEARN SAYRE MITOCHONDRIAL CYTOPATHY

  • jearn sayre mitochondrial cytopathy
  • mearn sayre mitochondrial cytopathy
  • learn sayre mitochondrial cytopathy
  • oearn sayre mitochondrial cytopathy
  • iearn sayre mitochondrial cytopathy
  • kwarn sayre mitochondrial cytopathy
  • ksarn sayre mitochondrial cytopathy
  • kdarn sayre mitochondrial cytopathy
  • krarn sayre mitochondrial cytopathy
  • k4arn sayre mitochondrial cytopathy
  • k3arn sayre mitochondrial cytopathy
  • kezrn sayre mitochondrial cytopathy
  • kesrn sayre mitochondrial cytopathy
  • kewrn sayre mitochondrial cytopathy
  • keqrn sayre mitochondrial cytopathy
  • keaen sayre mitochondrial cytopathy
  • keadn sayre mitochondrial cytopathy
  • keafn sayre mitochondrial cytopathy
  • keatn sayre mitochondrial cytopathy
  • kea5n sayre mitochondrial cytopathy