LEYDIG CELL Meaning and
Definition
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Leydig cells, also known as interstitial cells of Leydig, are specialized endocrine cells found in the testes of males and play a crucial role in the production of testosterone. These cells are located within the connective tissue surrounding the seminiferous tubules in the testes. Leydig cells are responsible for secreting androgen hormones, specifically testosterone, which are essential for the development and maintenance of male reproductive organs.
The Leydig cells receive signals from luteinizing hormone (LH) secreted by the anterior pituitary gland in response to the gonadotropin-releasing hormone (GnRH) produced in the hypothalamus. This stimulation triggers the Leydig cells to synthesize and release testosterone into the surrounding tissues and bloodstream. Testosterone then acts on target cells within the testes, promoting spermatogenesis, the development of secondary sexual characteristics, and enhancing libido.
Leydig cells are distinguished by their large cytoplasmic volume and rounded or polygonal shape containing numerous lipid droplets and abundant smooth endoplasmic reticulum. They possess a well-developed system of internal membranes, including mitochondria and smooth-surfaced endoplasmic reticulum, which facilitate the production of testosterone.
Understanding the function and regulation of Leydig cells is essential in the diagnosis and treatment of various reproductive disorders, such as hypogonadism and infertility. In summary, Leydig cells are the primary source of testosterone production in males and play a key role in male reproductive development and function.
Common Misspellings for LEYDIG CELL
- keydig cell
- peydig cell
- oeydig cell
- lwydig cell
- lsydig cell
- ldydig cell
- lrydig cell
- l4ydig cell
- l3ydig cell
- letdig cell
- legdig cell
- lehdig cell
- leudig cell
- le7dig cell
- le6dig cell
- leysig cell
- leyxig cell
- leycig cell
- leyfig cell
Etymology of LEYDIG CELL
The term "Leydig cell" is named after the German anatomist Franz Leydig, who discovered these specialized cells in the testicles of mammals in the late 19th century. Leydig cells are responsible for producing testosterone, the primary male sex hormone. Therefore, in recognition of his significant contribution to the field of reproductive biology, these cells were named after Dr. Franz Leydig.
