Pronunciation: [mˈə͡ʊbɪəs dɪzˈiːz] (IPA)

Moebius disease, also known as Moebius syndrome, is a rare neurological disorder that affects the muscles responsible for eye and facial movements. The spelling of "Moebius" may seem unusual, but it is derived from the name of the German neurologist Paul Julius Möbius. The IPA phonetic transcription for "Moebius" is /ˈmeɪbiəs/, with emphasis on the first syllable and a short "a" sound in the second syllable. Despite the unconventional spelling, the correct pronunciation of "Moebius" is similar to the word "may-bee-us".

MOEBIUS DISEASE Meaning and Definition

  1. Moebius disease, also known as Moebius syndrome, is a rare congenital neurological disorder characterized by the absence or underdevelopment of the sixth and seventh cranial nerves, which control the movements of the face. This condition affects the muscles that control facial expressions and eye movements. Moebius disease can also impact other cranial nerves, leading to various additional symptoms.

    Individuals with Moebius disease often present with facial paralysis from birth, with the inability to smile, frown, or even close their eyes fully. As a result, affected individuals may have difficulty making eye contact and expressing emotions through facial expressions. Other common features of the disorder include crossed or misaligned eyes, drooling, difficulty with speech articulation, and hearing impairments. Some individuals may also experience limb abnormalities and other neuromuscular or musculoskeletal conditions.

    The exact cause of Moebius disease is not fully understood. It is believed to result from a combination of genetic and environmental factors, possibly including prenatal or early developmental issues. There is no cure for Moebius disease, but various therapies and treatments can help manage the symptoms and improve quality of life. These may include physiotherapy, speech therapy, occupational therapy, and surgical interventions to correct limb abnormalities or improve mobility.

    Due to its rarity, Moebius disease affects individuals differently, and symptoms can vary in severity. Support groups and organizations exist to provide resources, education, and emotional support to individuals with Moebius disease and their families.

  2. Ophthalmoplegic migraine or periodical oculomotor paralysis.

    A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for MOEBIUS DISEASE

  • noebius disease
  • koebius disease
  • joebius disease
  • miebius disease
  • mkebius disease
  • mlebius disease
  • mpebius disease
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  • mowbius disease
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  • mo4bius disease
  • mo3bius disease
  • moevius disease
  • moenius disease
  • moehius disease
  • moegius disease
  • moebuus disease


The word "Moebius disease" derives its name from the German neurologist Paul Julius Möbius, who first described the condition in 1888. Paul Julius Möbius was known for his extensive work in neurology and psychiatry, and his name was given to this particular disorder as a tribute to his contributions in the field.