How Do You Spell OSLER'S DISEASE?

Pronunciation: [ˈɒsləz dɪzˈiːz] (IPA)

Osler's disease, also known as hereditary hemorrhagic telangiectasia (HHT), is a rare inherited condition that affects blood vessels. The correct spelling of this condition can be a bit tricky as it includes some unusual letter combinations. The word "Osler" is pronounced [ˈɑz-lər] and is spelled with an "O," not a "U" as it may be mistakenly written. The disease is spelled with two "Ls" and not one - it is Osler's, not Oser's. The phonetic transcription of Osler's disease is [ˈɑz-lərz dɪˈziz].

OSLER'S DISEASE Meaning and Definition

  1. Osler's disease, also known as hereditary hemorrhagic telangiectasia (HHT), is a rare genetic disorder characterized by the development of abnormal blood vessels in various organs of the body. This condition is named after William Osler, a Canadian physician who first described it in the late 19th century.

    The primary characteristic of Osler's disease is the formation of fragile, dilated blood vessels called telangiectasias. These telangiectasias primarily affect the skin and mucous membranes, particularly in the nose, lips, mouth, and fingertips. As a result, affected individuals may experience recurrent nosebleeds, known as epistaxis, and have a higher risk of developing gastrointestinal bleeding.

    The abnormal blood vessels associated with Osler's disease can also affect other organs, such as the lungs, liver, brain, and spine. This can lead to various complications depending on the affected organ, including pulmonary arteriovenous malformations (abnormal connections between arteries and veins in the lungs), liver and brain arteriovenous malformations, and spinal arteriovenous malformations.

    Other symptoms and features of Osler's disease may include anemia, fatigue, shortness of breath, chest pain, headaches, and neurological problems. The severity of symptoms can vary widely among affected individuals, even within the same family.

    Osler's disease is usually inherited in an autosomal dominant pattern, which means that individuals with a parent affected by the condition have a 50% chance of inheriting the genetic mutation responsible. Genetic testing can be performed to confirm a diagnosis of Osler's disease, particularly for individuals with a family history of the condition.

    Although there is currently no cure for Osler's disease, treatment focuses on managing symptoms and reducing complications.

  2. Polycythemia megalosplenica or polycythemia rubra megalosplenica, an affection marked by increase in the number of red blood-corpuscles, enlargement of the spleen, and cyanosis of the skin and mucous membranes. Cf. Vaquez's disease.

    A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for OSLER'S DISEASE

  • isler's disease
  • ksler's disease
  • lsler's disease
  • psler's disease
  • 0sler's disease
  • 9sler's disease
  • oaler's disease
  • ozler's disease
  • oxler's disease
  • odler's disease
  • oeler's disease
  • owler's disease
  • osker's disease
  • osper's disease
  • osoer's disease
  • oslwr's disease
  • oslsr's disease
  • osldr's disease
  • oslrr's disease
  • osl4r's disease

Etymology of OSLER'S DISEASE

The term "Osler's disease" is named after Sir William Osler, a Canadian physician who is often referred to as the "father of modern medicine". However, it is important to note that "Osler's disease" does not describe a specific medical condition; instead, it is a general term used to reference any disease that is associated with Osler's work or research.

Sir William Osler made significant contributions to the field of medicine and was a pioneer in clinical teaching and medical research. He had a particular interest in the study of cardiovascular diseases, including disorders that affect blood vessels such as arteriovenous malformations (AVMs).

The term "Osler's disease" is commonly used to describe a hereditary condition called hereditary hemorrhagic telangiectasia (HHT) or Osler-Weber-Rendu syndrome.

Infographic

Add the infographic to your website: