Oxiclozanidum is an active pharmaceutical ingredient (API) used in veterinary medicine. It belongs to the chemical class of salicylanilides and is primarily used as an anthelmintic drug in the treatment of parasitic infections in animals, particularly in livestock.
As a member of the salicylanilides group, oxiclozanidum works by interfering with the energy metabolism of parasites, specifically worms, thereby preventing their growth and reproduction. It exerts its anthelmintic effects by inhibiting the activity of succinate dehydrogenase in the mitochondria of the parasites. This disruption ultimately leads to the death of the parasites.
Oxiclozanidum is commonly administered orally, either in the form of tablets or suspensions, for the treatment and control of various gastrointestinal nematodes, notably those found in cattle, sheep, goats, and pigs. These parasites primarily include species such as Haemonchus, Ostertagia, Trichostrongylus, and Nematodirus.
Oxiclozanidum is generally well-tolerated and has a wide safety margin, making it suitable for use in animals. However, as with any medication, it may cause adverse reactions in some individuals, such as gastrointestinal disturbances or allergic reactions. Therefore, it is important to follow the recommended dosages and consult a veterinarian before administering oxiclozanidum to animals.
In conclusion, oxiclozanidum is an anthelmintic drug used in veterinary medicine to treat and control parasitic infections in livestock. Its mechanism of action involves disrupting the energy metabolism of parasites, leading to their death.
