P HYDROXYPHENYLPYRUVATE HYDROXYLASE Meaning and
Definition
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P Hydroxyphenylpyruvate Hydroxylase is an enzyme that plays a crucial role in the metabolic pathway known as tyrosine catabolism. This pathway is responsible for the breakdown of tyrosine, an amino acid, into other compounds that have various biological functions. The enzyme specifically catalyzes the hydroxylation of p-hydroxyphenylpyruvate (HPP) to form homogentisate.
P Hydroxyphenylpyruvate Hydroxylase is a member of the class of oxidoreductases, which are enzymes that facilitate oxidation-reduction reactions by catalyzing the transfer of electrons from one molecule to another. In this case, P Hydroxyphenylpyruvate Hydroxylase uses molecular oxygen as a co-substrate and transfers one of its oxygen atoms to the HPP molecule, resulting in the formation of homogentisate.
The enzyme is located in the mitochondria, the energy-producing organelles within cells. It is an iron-containing enzyme, with ferrous iron as a cofactor that is essential for its catalytic activity. P Hydroxyphenylpyruvate Hydroxylase is highly specific to its substrate and does not act on any other compounds in the tyrosine catabolic pathway.
Mutations in the gene encoding P Hydroxyphenylpyruvate Hydroxylase can lead to a rare genetic disorder called hereditary tyrosinemia type III. This condition is characterized by an accumulation of HPP and other tyrosine metabolites in the body, which can result in various health problems such as liver dysfunction, intellectual disability, and elevated levels of tyrosine in the blood.
Common Misspellings for P HYDROXYPHENYLPYRUVATE HYDROXYLASE
- o hydroxyphenylpyruvate hydroxylase
- l hydroxyphenylpyruvate hydroxylase
- - hydroxyphenylpyruvate hydroxylase
- 0 hydroxyphenylpyruvate hydroxylase
- p gydroxyphenylpyruvate hydroxylase
- p bydroxyphenylpyruvate hydroxylase
- p nydroxyphenylpyruvate hydroxylase
- p jydroxyphenylpyruvate hydroxylase
- p uydroxyphenylpyruvate hydroxylase
- p yydroxyphenylpyruvate hydroxylase
- p htdroxyphenylpyruvate hydroxylase
- p hgdroxyphenylpyruvate hydroxylase
- p hhdroxyphenylpyruvate hydroxylase
- p hudroxyphenylpyruvate hydroxylase
- p h7droxyphenylpyruvate hydroxylase
- p h6droxyphenylpyruvate hydroxylase
- p hysroxyphenylpyruvate hydroxylase
- p hyxroxyphenylpyruvate hydroxylase
- p hycroxyphenylpyruvate hydroxylase
- p hyfroxyphenylpyruvate hydroxylase
