How Do You Spell P450SCC?

Pronunciation: [pˈiː fˈɔːhˈʌndɹədən fˈɪfti ˌɛssˌiːsˈiː] (IPA)

The word "P450SCC" is a scientific term used in the field of biochemistry. This term refers to a cytochrome P450 enzyme that is involved in steroid hormone synthesis. The spelling of this word can be explained using the International Phonetic Alphabet (IPA). The "P" is pronounced as "pi", the "4" is pronounced as "fɔː", the "5" is pronounced as "faɪv", the "0" is pronounced as "ˈzɪrəʊ", the "S" is pronounced as "ɛs", the "C" is pronounced as "si", and the final "C" is pronounced as "si".

P450SCC Meaning and Definition

  1. P450SCC stands for Cytochrome P450 side-chain cleavage enzyme. It is an enzyme found in a variety of organisms, including humans, that is involved in the conversion of cholesterol to pregnenolone, a precursor molecule for the synthesis of various steroid hormones.

    The P450SCC enzyme is a member of the cytochrome P450 superfamily, a group of enzymes that play a crucial role in the metabolism of a wide range of compounds in the body. It is primarily located in the mitochondria of steroidogenic tissues, such as the adrenal glands and gonads.

    The main function of P450SCC is to catalyze the cleavage of the side-chain of cholesterol, which results in the formation of pregnenolone. This reaction is the rate-limiting step in the synthesis of steroid hormones, including glucocorticoids, mineralocorticoids, and sex steroids.

    The activity of P450SCC is tightly regulated by various factors, including hormonal stimuli and levels of cholesterol in the cells. Mutations or deficiencies in the P450SCC enzyme can cause disorders of steroid hormone synthesis, leading to various clinical manifestations.

    In addition to its role in steroidogenesis, P450SCC also has been found to have some non-steroidogenic functions. These include the metabolism of xenobiotic compounds (foreign substances) and the regulation of cellular oxidative stress.

    Overall, P450SCC is an essential enzyme involved in the biosynthesis of steroid hormones, playing a crucial role in maintaining hormonal balance and regulating various physiological processes in the body.

Common Misspellings for P450SCC

  • o450scc
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  • p450scx
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  • p450scd
  • op450scc
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  • pl450scc
  • -p450scc
  • p-450scc
  • 0p450scc
  • p0450scc
  • p3450scc
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  • p4t50scc
  • p45t0scc
  • p4650scc
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  • p45o0scc
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  • p45-0scc
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  • p450ascc
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  • p450scxc
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  • r450SCC
  • q450SCC
  • Pt50SCC
  • P050SCC
  • P650SCC
  • P4u0SCC
  • P410SCC
  • P470SCC
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  • P454SCC
  • P452SCC
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  • P450cCC
  • P450qCC
  • P450rCC
  • P450SsC
  • P450SkC
  • P450SgC
  • P450SaC
  • P450SbC
  • P450SCs
  • P450SCk
  • P450SCg
  • P450SCa
  • P450SCb
  • p4 50scc
  • p450s cc
  • p450sc c

Etymology of P450SCC

The term "P450SCC" is a combination of two key components - "P450" and "SCC"."P450" refers to a group of enzymes called cytochrome P450 enzymes. The term "P450" stands for "pigment 450", as these enzymes were initially discovered due to their ability to absorb light at a wavelength of 450nm. They are a superfamily of heme-containing enzymes that play a crucial role in various biological processes, including drug metabolism, hormone synthesis, and detoxification in organisms."SCC" specifically refers to the enzyme side-chain cleavage enzyme, which is also known as cytochrome P450 side-chain cleavage enzyme. This particular enzyme, P450SCC, is involved in the conversion of cholesterol to pregnenolone, which is a crucial step in the synthesis of various steroid hormones, including cortisol, aldosterone, and sex hormones like estrogen and testosterone.

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