How Do You Spell PARP?

Pronunciation: [pˈɑːp] (IPA)

The spelling of the word "PARP" is quite straightforward once you understand the International Phonetic Alphabet (IPA). IPA transcription for "PARP" begins with the consonant sound "p" followed by the vowel sound "a" that is pronounced with an open mouth. The spelling continues with "r," which is pronounced in the back of the mouth, and "p" again. So, the correct IPA transcription for "PARP" is /pɑrp/. This simple four-letter word may have various meanings and usages depending on context.

Meaning and Definition
Common Misspellings
Conjugate verb
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PARP Meaning and Definition

  1. PARP stands for Poly ADP-Ribose Polymerase, which is an enzyme involved in DNA repair mechanisms in cells. PARP plays a critical role in the recognition and repair of DNA damage, especially single-strand breaks (SSBs). This enzyme is responsible for attaching poly ADP-ribose (PAR) chains to target proteins, facilitating the recruitment of repair factors to damaged sites and assisting in the restoration of DNA integrity.

    PARP is a crucial component in cellular processes such as base excision repair and homologous recombination. By binding to the DNA strand break site, PARP initiates the repair process by catalyzing the synthesis of PAR chains. These chains serve as a scaffold to attract proteins involved in DNA repair, including helicases, polymerases, and DNA ligases.

    In addition to its role in DNA repair, PARP also plays a role in cellular stress response and programmed cell death, known as apoptosis. PARP activation regulates the balance between DNA repair and cell death pathways, determining cell survival or cell death. Consequently, PARP inhibitors have emerged as promising therapeutic agents for various cancers, particularly those with DNA repair defects.

    In conclusion, PARP is an enzyme that plays a vital role in DNA repair by attaching PAR chains to target proteins at sites of DNA damage, facilitating the recruitment of repair factors. Its involvement extends beyond DNA repair, with implications in cellular stress response and apoptosis.

Common Misspellings for PARP

  • 0arp
  • pzrp
  • pwrp
  • pa5p
  • pa4p
  • par0
  • oparp
  • p-arp
  • 0parp
  • p0arp
  • pzarp
  • pazrp
  • pasrp
  • pwarp
  • pawrp
  • pqarp
  • paqrp
  • paerp
  • padrp
  • pafrp
  • parfp
  • patrp
  • partp
  • pa5rp
  • par5p
  • pa4rp
  • par4p
  • parpo
  • parlp
  • par-p
  • par0p
  • parp0
  • pparp
  • paarp
  • parrp
  • parpp
  • pa rp

Conjugate verb Parp

CONDITIONAL

I would parp
you would parp
he/she/it would parp
we would parp
they would parp

CONDITIONAL CONTINUOUS

I would be parping
you would be parping
he/she/it would be parping
we would be parping
they would be parping

CONDITIONAL PERFECT

I would have parp
you would have parp
he/she/it would have parp
we would have parp
they would have parp

CONDITIONAL PERFECT CONTINUOUS

I would have been parping
you would have been parping
he/she/it would have been parping
we would have been parping
they would have been parping

FUTURE

I will parp
you will parp
he/she/it will parp
we will parp
they will parp

FUTURE CONTINUOUS

I will be parping
you will be parping
he/she/it will be parping
we will be parping
they will be parping

FUTURE PERFECT

I will have parped
you will have parped
he/she/it will have parped
we will have parped
they will have parped

FUTURE PERFECT CONTINUOUS

I will have been parping
you will have been parping
he/she/it will have been parping
we will have been parping
they will have been parping

IMPERATIVE

you parp
we let´s parp

NONFINITE VERB FORMS

to parp

PAST

I parped
you parped
he/she/it parped
we parped
they parped

PAST CONTINUOUS

I was parping
you were parping
he/she/it was parping
we were parping
they were parping

PAST PARTICIPLE

parped

PAST PERFECT

I had parped
you had parped
he/she/it had parped
we had parped
they had parped

PAST PERFECT CONTINUOUS

I had been parping
you had been parping
he/she/it had been parping
we had been parping
they had been parping

PRESENT

I parp
you parp
he/she/it parps
we parp
they parp

PRESENT CONTINUOUS

I am parping
you are parping
he/she/it is parping
we are parping
they are parping

PRESENT PARTICIPLE

parping

PRESENT PERFECT

I have parped
you have parped
he/she/it has parped
we have parped
they have parped

PRESENT PERFECT CONTINUOUS

I have been parping
you have been parping
he/she/it has been parping
we have been parping
they have been parping

Infographic

Correct spelling for PARP
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