PCTUBULIN Meaning and
Definition
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PCTUBULIN refers to the protein known as pericentriolar material 1 (PCM1) tumor suppressor protein, which is also commonly referred to as pericentrin. As a protein found in the pericentriolar material, PCTUBULIN plays a crucial role in the organization of microtubules, which are structural components vital for various cellular processes such as cell division, intracellular transport, and cell shape maintenance.
PCTUBULIN is primarily located in the pericentrosomal matrix surrounding the centrosome, a microtubule-organizing center found near the nucleus of animal cells. It functions as a scaffold protein, contributing to the stability and integrity of the centrosome as well as the formation of functional microtubule-organizing centers. PCTUBULIN works in conjunction with other proteins to ensure the correct assembly and arrangement of microtubules during cell division, playing a crucial role in the mitotic spindle formation and accurate chromosome segregation.
Beyond its structural functions, PCTUBULIN has also been identified as a tumor suppressor protein and is associated with various cellular mechanisms involved in preventing the development of cancer. Mutations or loss of PCTUBULIN expression have been linked to the formation of abnormal centrosomes, genomic instability, and increased susceptibility to genetic abnormalities that contribute to carcinogenesis.
Understanding the functions of PCTUBULIN is essential for deciphering the intricate processes associated with microtubule organization, cell division, and tumor suppression mechanisms, thereby offering insights into both normal cellular functions and the dysregulation observed in various diseases, particularly cancer.
Common Misspellings for PCTUBULIN
- octubulin
- lctubulin
- -ctubulin
- 0ctubulin
- pxtubulin
- pvtubulin
- pftubulin
- pdtubulin
- pcrubulin
- pcfubulin
- pcgubulin
- pcyubulin
- pc6ubulin
- pc5ubulin
- pctybulin
- pcthbulin
- pctjbulin
- pctibulin
- pct8bulin
- pct7bulin
