PYRIDINONES Meaning and
Definition
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Pyridinones are a class of organic compounds characterized by a pyridine ring fused with a lactam moiety, which is a cyclic amide. The pyridinone structure consists of a six-membered nitrogen-containing heterocycle (pyridine) fused with a lactam ring, resulting in a unique fused-ring structure.
Pyridinones exhibit a wide range of chemical and biological properties, making them important building blocks in organic synthesis and medicinal chemistry. They are usually synthesized through the cyclization of appropriate precursors, such as amides or amine derivatives, using various synthetic strategies.
In terms of their chemical properties, pyridinones display aromaticity due to the presence of the pyridine ring, conferring stability and resonance effects. This aromaticity allows for their participation in a variety of chemical reactions, including electrophilic substitution, nucleophilic addition, and metal coordination.
Pyridinones have found diverse applications in medicinal chemistry due to their ability to interact with biological targets. They can act as versatile scaffolds for the design and development of drugs, as they can modulate or inhibit protein targets involved in various diseases, including cancer, neurodegenerative disorders, and infectious diseases.
In conclusion, pyridinones are a class of organic compounds characterized by a fused-ring system comprising a pyridine ring and a lactam moiety. They possess aromaticity, exhibit a range of chemical reactivity, and have versatile applications in organic synthesis and medicinal chemistry.
Common Misspellings for PYRIDINONES
- oyridinones
- lyridinones
- -yridinones
- 0yridinones
- ptridinones
- pgridinones
- phridinones
- puridinones
- p7ridinones
- p6ridinones
- pyeidinones
- pydidinones
- pyfidinones
- pytidinones
- py5idinones
- py4idinones
- pyrudinones
- pyrjdinones
- pyrkdinones
- pyrodinones
Etymology of PYRIDINONES
The term "pyridinones" is derived from the combination of two different words: "pyridine" and "one".
1. Pyridine: The word "pyridine" refers to a heterocyclic organic compound that has a six-membered ring made up of five carbon atoms and one nitrogen atom. The name "pyridine" originates from the fact that it is structurally related to benzene, but with one carbon atom replaced by a nitrogen atom.
2. One: The word "one" is an idiomatic usage in organic chemistry, typically used to describe a compound that contains a ketone functional group, which consists of a carbonyl group (C=O) bonded to two other carbon atoms.
When these two terms are combined, "pyridinones" refers to a class of organic compounds that share the pyridine ring structure and contain a ketone functional group.
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