SEGMENTAL HYALINOSIS Meaning and
Definition
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Segmental hyalinosis is a medical condition characterized by the accumulation of hyaline material within the walls of small blood vessels, resulting in their thickening and narrowing. The term "segmental" refers to the localized and patchy distribution of the hyaline deposits in affected tissues.
Hyaline material is a translucent, glassy substance composed of various proteins and is typically found in damaged or degenerating tissues. In the case of segmental hyalinosis, the hyaline accumulates specifically in the blood vessels, leading to their structural abnormalities.
The narrowing of blood vessel lumens caused by segmental hyalinosis can result in reduced blood flow to the organs and tissues supplied by these vessels. This impaired blood supply may lead to ischemia, tissue damage, and dysfunction.
Segmental hyalinosis can occur in various organs, including the kidneys, gastrointestinal tract, skin, and lungs. In the kidneys, a form of segmental hyalinosis known as focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic syndrome, a kidney disorder characterized by proteinuria (excessive protein in the urine), edema, hypoalbuminemia (low levels of albumin in the blood), and hyperlipidemia (elevated levels of lipids in the blood).
The exact cause of segmental hyalinosis is often unknown, although it may be secondary to other underlying conditions, such as immunological disorders, hypertension, diabetes mellitus, or exposure to certain toxins. Treatment options for segmental hyalinosis generally focus on addressing the underlying cause, managing symptoms, and preserving organ function.
Common Misspellings for SEGMENTAL HYALINOSIS
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Etymology of SEGMENTAL HYALINOSIS
The term "Segmental Hyalinosis" consists of two separate parts:
1. Segmental: This word is derived from the Latin term "segmentum", meaning a section or a part. In medical terminology, "segmental" refers to the involvement of a specific section or segment of an organ or tissue.
2. Hyalinosis: This word is derived from the Greek term "hyalinos", meaning glass. In medical terms, "hyalinosis" refers to the deposition or formation of a glassy or transparent substance, known as hyaline, in the tissues.
Therefore, "Segmental Hyalinosis" refers to the deposition of a glassy or transparent substance within a specific segment or section of an organ or tissue.
