Pronunciation: [tˈiː fˈɔː mˈɒnə͡ʊdˌe͡ɪədˌɪne͡ɪs] (IPA)

The term "T4 Monodeiodinase" refers to an enzyme involved in the conversion of thyroid hormones. The word is spelled as "ti-for mono-die-oh-di-nase." The IPA phonetic transcription reflects the pronunciation of each syllable. The "T4" refers to thyroxine, a thyroid hormone, which is modified by the enzyme. The enzyme's name is derived from the term "monodeiodination," which means the removal of one iodine atom. Proper spelling and pronunciation of scientific terms is essential for effective communication among researchers and medical professionals.

T4 MONODEIODINASE Meaning and Definition

  1. T4 Monodeiodinase is an enzyme that plays a crucial role in the regulation of thyroid hormone levels in the body. It is primarily responsible for the conversion of the prohormone thyroxine (T4) into the active form of thyroid hormone known as triiodothyronine (T3). This enzymatic process, called deiodination, involves the removal of one iodine atom from the T4 molecule.

    T4 Monodeiodinase is found in various tissues throughout the body, including the liver, kidneys, and thyroid gland. It is especially abundant in target tissues that are sensitive to thyroid hormone, such as the brain, heart, and skeletal muscles. The activity of this enzyme directly influences the availability and metabolism of T3, which is essential for the regulation of metabolism, growth, and development.

    Abnormalities in T4 Monodeiodinase activity can have significant physiological consequences. For instance, decreased activity of the enzyme can lead to reduced T3 production, resulting in a condition known as hypothyroidism. On the other hand, excessive activity of T4 Monodeiodinase can lead to increased T3 production, causing symptoms of hyperthyroidism.

    Overall, T4 Monodeiodinase serves as a critical mediator in the conversion of thyroxine into the physiologically active thyroid hormone, triiodothyronine. Its precise regulation ensures the appropriate functioning of the thyroid gland and optimal overall health.

Common Misspellings for T4 MONODEIODINASE

  • r4 monodeiodinase
  • f4 monodeiodinase
  • g4 monodeiodinase
  • y4 monodeiodinase
  • 64 monodeiodinase
  • 54 monodeiodinase
  • t3 monodeiodinase
  • te monodeiodinase
  • tr monodeiodinase
  • t5 monodeiodinase
  • t4 nonodeiodinase
  • t4 konodeiodinase
  • t4 jonodeiodinase
  • t4 minodeiodinase
  • t4 mknodeiodinase
  • t4 mlnodeiodinase
  • t4 mpnodeiodinase
  • t4 m0nodeiodinase
  • t4 m9nodeiodinase
  • t4 mobodeiodinase


The word "T4 Monodeiodinase" is formed through a combination of different elements:

1. T4: T4 is short for thyroxine, which is a hormone produced by the thyroid gland. It is also known as tetraiodothyronine. The "T4" part in the term "T4 Monodeiodinase" refers to the specific hormone that this enzyme acts upon.

2. Monodeiodinase: The suffix "-ase" in biology refers to an enzyme, which is a protein that catalyzes a specific biochemical reaction. "Monodeiodinase" refers to the action of removing one iodine atom from a molecule. In this context, it specifically refers to an enzyme that is responsible for converting the thyroid hormone T4 into the active form T3 (triiodothyronine) by removing one iodine atom.