How Do You Spell TERMINATOR SEQUENCE?

Pronunciation: [tˈɜːmɪnˌe͡ɪtə sˈiːkwəns] (IPA)

The commonly known term "Terminator Sequence" in genetics is sometimes mistakenly spelled as "Termenator Sequence". The correct pronunciation and spelling of this word are crucial in the field of molecular biology as it refers to a sequence of nucleotides that signals the termination of DNA transcription. The correct phonetic transcription for "Terminator Sequence" is /tərˈmɪnətər ˈsiːkwəns/ (tuh-min-uh-ter see-kwuns), emphasizing the correct pronunciation of the word's syllables and stress.

TERMINATOR SEQUENCE Meaning and Definition

1. Terminator Sequence refers to a concept mainly used in genetics and molecular biology to describe a specific DNA sequence that signals the termination of transcription. Transcription is a process in which genetic information encoded in DNA is converted into RNA molecules. The Terminator Sequence plays a crucial role in this process by marking the end point at which the RNA polymerase enzyme halts transcription.

   In eukaryotes, the Terminator Sequence is commonly found in the form of a specific DNA nucleotide sequence located downstream from the coding region of a gene. Once the RNA polymerase reaches this sequence, it recognizes it as a termination signal and subsequently detaches from the DNA template. This detachment prevents further transcription of the DNA sequence into an RNA molecule.

   The Terminator Sequence is essential to ensure accurate and precise transcription termination. It helps prevent overlapping of genes and ensures the formation of fully functional RNA molecules. The specific nucleotide sequence of the Terminator Sequence varies across different organisms and can include characteristic motifs or structures that promote termination.

   Understanding Terminator Sequences is crucial in studying gene expression and regulation. Manipulating or modifying these sequences can have significant implications in various fields, such as genetic engineering and biotechnology. Consequently, the discovery and characterization of Terminator Sequences have greatly contributed to our understanding of the intricate processes involved in gene transcription and regulation.

Common Misspellings for TERMINATOR SEQUENCE

• rerminator sequence
• ferminator sequence
• germinator sequence
• yerminator sequence
• 6erminator sequence
• 5erminator sequence
• twrminator sequence
• tsrminator sequence
• tdrminator sequence
• trrminator sequence
• t4rminator sequence
• t3rminator sequence
• teeminator sequence
• tedminator sequence
• tefminator sequence
• tetminator sequence
• te5minator sequence
• te4minator sequence
• terninator sequence
• terkinator sequence

Etymology of TERMINATOR SEQUENCE

The term "Terminator Sequence" has its origins in the field of molecular biology, specifically in DNA sequencing. The word "Terminator" refers to the segment of DNA sequence that signals the end of a gene or a specific region of DNA.

In DNA sequencing, scientists use a method called Sanger sequencing, which involves DNA replication and the incorporation of chain-terminating dideoxynucleotides (ddNTPs) during the replication process. These ddNTPs lack a 3'-OH group required for the addition of subsequent nucleotides, causing DNA synthesis to stop and terminate at the point where they are incorporated.

The resulting DNA fragments, each ending with a different ddNTP, are then separated using gel electrophoresis. As a result, a series of fragments is obtained, with each fragment representing a different nucleotide position within the original DNA sequence.