TRP TRNA LIGASE Meaning and
Definition
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Trp tRNA ligase, also known as tryptophan-transfer RNA ligase, is an enzyme that plays a vital role in the production of proteins. It belongs to the ligase family and specifically functions to catalyze the formation of a covalent bond between tryptophan amino acid and its corresponding transfer RNA (tRNA) molecule during the process of protein synthesis.
This enzyme is responsible for attaching tryptophan to a specific nucleotide sequence on the tRNA molecule, known as the anticodon, which is complementary to the codon found on messenger RNA (mRNA). By connecting tryptophan to tRNA, Trp tRNA ligase ensures that the correct amino acid is incorporated into the growing polypeptide chain during translation.
The Trp tRNA ligase enzyme undergoes a series of coordinated steps to accomplish this reaction. First, it activates tryptophan by binding it with adenosine triphosphate (ATP), forming an aminoacyl-adenylate intermediate. Then, it transfers the activated tryptophan to the tRNA's 3'-end, generating an ester bond between the amino acid and tRNA.
The precise functioning of Trp tRNA ligase is crucial for maintaining the fidelity of protein synthesis, as any error in attaching the incorrect amino acid to the tRNA can result in a defective or non-functional protein. Therefore, the accurate and efficient activity of Trp tRNA ligase is necessary for the proper functioning of cellular processes and overall protein integrity.
Common Misspellings for TRP TRNA LIGASE
- rrp trna ligase
- frp trna ligase
- grp trna ligase
- yrp trna ligase
- 6rp trna ligase
- 5rp trna ligase
- tep trna ligase
- tdp trna ligase
- tfp trna ligase
- ttp trna ligase
- t5p trna ligase
- t4p trna ligase
- tro trna ligase
- trl trna ligase
- tr- trna ligase
- tr0 trna ligase
- trp rrna ligase
- trp frna ligase
- trp grna ligase
- trp yrna ligase
