How Do You Spell URATE OXIDASE?

Pronunciation: [jˈʊ͡əɹe͡ɪt ˈɒksɪdˌe͡ɪs] (IPA)

The spelling of "Urate Oxidase" may seem complicated, but with the help of IPA phonetic transcription, it becomes easier to understand. This enzyme responsible for the breakdown of uric acid is pronounced as /jʊˈreɪt ˈɑːksɪdeɪz/. The "U" is pronounced as "yu", followed by the "r" sound with a short "e" vowel sound. The "ate" ending is pronounced as "ayt". The "Oxidase" is pronounced as "ok-si-deyz" with the emphasis on the second syllable. Knowing the correct pronunciation of "Urate Oxidase" is essential for researchers studying gout and other uric acid-related diseases.

URATE OXIDASE Meaning and Definition

1. Urate oxidase, also known as uricase, is an enzyme that plays a crucial role in the metabolism and elimination of uric acid from the body. Uric acid is a natural waste product that is formed as a result of the breakdown of purines, which are constituents of DNA and RNA. In normal circumstances, urate oxidase converts uric acid into allantoin, a much more soluble and easily excreted compound.

   Urate oxidase is primarily found in species such as birds and most mammals, with the notable exceptions of some primates, including humans. This implies that humans lack the physiological ability to produce urate oxidase. Consequently, humans primarily excrete uric acid in its original form, which is relatively less soluble and prone to crystallization. The accumulation of uric acid crystals in joints and tissues leads to the development of a medical condition known as gout.

   Due to the therapeutic potential of urate oxidase, artificial forms of the enzyme have been developed for medical application. Recombinant urate oxidase has been used in the treatment of conditions like chronic gout and tumor lysis syndrome, where high levels of uric acid accumulate and may cause significant health issues. By catalyzing the conversion of uric acid into allantoin, urate oxidase helps lower uric acid levels in the blood and reduces the risk of crystal formation.

   In summary, urate oxidase is an enzyme that breaks down uric acid into a more soluble form called allantoin. Its deficiency in humans contributes to the development of conditions such as gout, and the utilization of artificial forms of urate oxidase can aid in the management of related medical issues.

Common Misspellings for URATE OXIDASE

• yrate oxidase
• hrate oxidase
• jrate oxidase
• irate oxidase
• 8rate oxidase
• 7rate oxidase
• ueate oxidase
• udate oxidase
• ufate oxidase
• utate oxidase
• u5ate oxidase
• u4ate oxidase
• urzte oxidase
• urste oxidase
• urwte oxidase
• urqte oxidase
• urare oxidase
• urafe oxidase
• urage oxidase
• uraye oxidase

Etymology of URATE OXIDASE

The word "urate" comes from the Latin "uratus", which means "to make golden" or "to color with gold". It refers to the compound uric acid, a substance that can have a yellowish color.

The term "oxidase" is derived from the word "oxidation", which comes from the Latin "oxidare", meaning "to combine with oxygen". In biochemistry, an oxidase is an enzyme that catalyzes oxidation reactions by transferring oxygen atoms or electrons from a substrate to an acceptor molecule.

Therefore, "urate oxidase" refers to an enzyme that catalyzes the oxidation of uric acid by transferring oxygen atoms or electrons from uric acid to another molecule or compound.