How Do You Spell PDGF ALPHA RECEPTOR?

Pronunciation: [pˌiːdˌiːd͡ʒˌiːˈɛf ˈalfə ɹɪsˈɛptə] (IPA)

PDGF alpha receptor is a protein expressed on the surface of cells that binds to PDGF alpha molecules, playing a crucial role in cell proliferation and differentiation. The spelling of this word is best explained through IPA phonetic transcription: /piː diː dʒiː ɑːlfə rɪˈseptər/. The PDGF is pronounced as "pee-dee-jee," while "alpha" is pronounced as "alf-uh." The final consonants in "receptor" are pronounced separately, with the phoneme /p/ in "recep" and the phoneme /t/ in "tor." Overall, correct pronunciation and spelling of this term will ensure effective communication in the scientific community.

PDGF ALPHA RECEPTOR Meaning and Definition

  1. The PDGF alpha receptor refers to a specific cell surface protein that plays a significant role in cellular signaling and the transmission of growth signals. PDGF (platelet-derived growth factor) itself is a type of protein that is involved in various biological processes, such as cell division, cell growth, and tissue repair.

    The PDGF alpha receptor is part of the tyrosine kinase receptor family, which means it possesses an enzymatic activity that adds phosphate groups to specific tyrosine residues. This receptor is primarily found on the surface of certain cells, particularly those of mesenchymal origin, such as fibroblasts, smooth muscle cells, and certain types of cancer cells.

    When PDGF protein molecules bind to the PDGF alpha receptors, it triggers a cascade of intracellular events. This binding induces the activation of the receptor's tyrosine kinase activity, leading to the phosphorylation of specific tyrosine residues within the receptor. These phosphorylation events serve as docking sites for various intracellular signaling molecules, initiating a signaling pathway that regulates cell proliferation, migration, and differentiation.

    The PDGF alpha receptor plays a critical role in embryonic development, wound healing, and tissue remodeling. Dysregulation or overexpression of this receptor has been associated with several diseases, including cancers, fibrotic disorders, and certain cardiovascular diseases. Consequently, the PDGF alpha receptor is an attractive target for therapeutic interventions, and various drugs have been developed to modulate its activity and potentially treat these diseases.

Common Misspellings for PDGF ALPHA RECEPTOR

  • odgf alpha receptor
  • ldgf alpha receptor
  • -dgf alpha receptor
  • 0dgf alpha receptor
  • psgf alpha receptor
  • pxgf alpha receptor
  • pcgf alpha receptor
  • pfgf alpha receptor
  • prgf alpha receptor
  • pegf alpha receptor
  • pdff alpha receptor
  • pdvf alpha receptor
  • pdbf alpha receptor
  • pdhf alpha receptor
  • pdyf alpha receptor
  • pdtf alpha receptor
  • pdgd alpha receptor
  • pdgc alpha receptor
  • pdgv alpha receptor
  • pdgg alpha receptor

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