How Do You Spell PROCOLLAGEN TYPE VII?

Pronunciation: [pɹə͡ʊkˈɒle͡ɪd͡ʒən tˈa͡ɪp ɹˌə͡ʊmən sˈɛvən] (IPA)

Procollagen Type VII is a protein found in humans that is involved in the formation of collagen, a crucial component of connective tissues. The spelling of Procollagen Type VII can be broken down using the International Phonetic Alphabet (IPA), with "pro" being pronounced as /pɹəʊ/, "col" as /kɒl/, "la" as /lə/ and "gen" as /dʒɛn/. "Type" is pronounced as /taɪp/, and "VII" as /ˈsev.ən/. Understanding the pronunciation of this word is important for professionals in fields such as dermatology and biology.

PROCOLLAGEN TYPE VII Meaning and Definition

  1. Procollagen Type VII is a protein that plays a crucial role in the structure and function of connective tissues, particularly in the formation and maintenance of the skin, the basement membrane of various tissues, and the anchoring fibrils that connect the basement membrane to the underlying dermis. It is encoded by the COL7A1 gene.

    Procollagen Type VII belongs to the collagen family, which are a group of fibrous proteins that provide strength and support to various parts of the body. It is synthesized as procollagen, which consists of three polypeptide chains that intertwine to form a triple helix structure. During the processing and maturation of procollagen Type VII, specific enzymes cleave off the N-terminal and C-terminal domains, resulting in collagen molecules.

    The collagen molecules then self-assemble into fibrils, which serve as key structural components in tissues. In the case of collagen Type VII, these fibrils form anchoring fibrils that connect the basement membrane to the underlying dermis, providing stability and integrity to the skin and other tissues.

    Deficiencies or mutations in the COL7A1 gene can lead to various disorders, such as dystrophic epidermolysis bullosa (DEB), a rare genetic skin disorder characterized by easy blistering and skin fragility. Understanding the function and structure of Procollagen Type VII is essential for both the diagnosis and potential treatment options for these disorders.

Common Misspellings for PROCOLLAGEN TYPE VII

  • Procolhagen Type II
  • orocollagen type vii
  • lrocollagen type vii
  • -rocollagen type vii
  • 0rocollagen type vii
  • peocollagen type vii
  • pdocollagen type vii
  • pfocollagen type vii
  • ptocollagen type vii
  • p5ocollagen type vii
  • p4ocollagen type vii
  • pricollagen type vii
  • prkcollagen type vii
  • prlcollagen type vii
  • prpcollagen type vii
  • pr0collagen type vii
  • pr9collagen type vii
  • proxollagen type vii
  • provollagen type vii
  • profollagen type vii

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