Gold anti-inflammatory agents, also known as gold salts or gold therapy, are a class of pharmaceutical drugs derived from the metal gold. These agents have been used primarily for their potent anti-inflammatory properties, making them valuable in the treatment of various chronic inflammatory conditions, particularly rheumatoid arthritis.
These drugs work by targeting and inhibiting the body's immune responses, particularly suppressing the activity of certain immune cells known as T-lymphocytes and macrophages. By doing so, they help to control the inflammatory response, reducing pain, swelling, and joint damage associated with rheumatoid arthritis.
Gold anti-inflammatory agents can be administered orally or parenterally and are usually prescribed when other nonsteroidal anti-inflammatory drugs (NSAIDs) and disease-modifying antirheumatic drugs (DMARDs) have failed to provide sufficient relief. Their efficacy varies from patient to patient, requiring careful monitoring of the individual's response and potential side effects.
Although gold anti-inflammatory agents have been historically successful in treating rheumatoid arthritis, their use has diminished in recent years due to the emergence of newer, more targeted therapies. However, they may still be considered in certain cases, especially for patients who are intolerant or unresponsive to other treatment options.
Common side effects of gold anti-inflammatory agents include skin reactions, mouth ulcers, kidney problems, and blood disorders. Therefore, close medical supervision is necessary during treatment with gold salts to evaluate their benefits and manage any adverse reactions.
